Less Invasive Surgery for Early Stage Cervical Cancer
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Conservative Surgery for early-stage cervical cancer?
Is less invasive surgery for early-stage cervical cancer safe?
How is conservative surgery different from other treatments for early-stage cervical cancer?
Conservative surgery for early-stage cervical cancer is less invasive than traditional radical hysterectomy, aiming to reduce surgical complications while preserving fertility. It involves procedures like conization (removal of a cone-shaped section of the cervix) and trachelectomy (removal of the cervix while keeping the uterus), often combined with lymph node assessment, and is considered safe for selected patients.26111213
What is the purpose of this trial?
This clinical trial studies conservative surgery in treating patients with low-risk stage IA2 or IB1 cervical cancer. Conservative surgery is a less invasive type of surgery for early stage cervical cancer and may have fewer side effects and improve recovery.
Research Team
Kathleen M Schmeler
Principal Investigator
M.D. Anderson Cancer Center
Eligibility Criteria
This trial is for women with early-stage cervical cancer (stage IA2 or IB1) that's less than 2 cm in size, without high-risk features like certain aggressive cell types or deep invasion into the cervix. Participants should not have had previous major treatments for their condition and must test negative for cancer spread.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Patients undergo a complete lymphatic mapping with sentinel lymph node biopsy and/or pelvic lymph node dissection. If future fertility is no longer desired, patients also undergo hysterectomy with or without bilateral salpingo-oophorectomy.
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Conservative Surgery
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator