Exercise training for Diabetes

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Diabetes+2 MoreExercise training - Other
Eligibility
18 - 50
All Sexes
What conditions do you have?
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Study Summary

This trial is investigating the role of glycosphingolipids (GSLs) in the development of type II diabetes and cardiovascular disease. They will test the hypotheses that exercise and weight loss interventions will reduce the levels of GSLs in obese diabetic patients and alleviate vascular risk.

Eligible Conditions
  • Diabetes
  • Obesity
  • Cardiovascular Disease

Treatment Effectiveness

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 4 years

4 years
Activation Analysis
Brachial artery flow-mediated dilation (percent vasodilation) in 60 obese diabetic subjects
Structure of brachial artery
Glycosphingolipid content (ng/ml) in adiposomes from 60 obese diabetic subjects

Trial Safety

Trial Design

2 Treatment Groups

Control (standards of care)
1 of 2
Exercise training
1 of 2

Active Control

Experimental Treatment

60 Total Participants · 2 Treatment Groups

Primary Treatment: Exercise training · No Placebo Group · N/A

Exercise training
Other
Experimental Group · 1 Intervention: Exercise training · Intervention Types: Other
Control (standards of care)NoIntervention Group · 1 Intervention: Control (standards of care) · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 4 years

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)NIH
3,588 Previous Clinical Trials
46,945,939 Total Patients Enrolled
28 Trials studying Diabetes
41,900 Patients Enrolled for Diabetes
University of Illinois at ChicagoLead Sponsor
537 Previous Clinical Trials
1,550,545 Total Patients Enrolled
2 Trials studying Diabetes
3,762 Patients Enrolled for Diabetes
Abeer M Mohamed, MD, PhDPrincipal InvestigatorUniversity of Illinois at Chicago

Eligibility Criteria

Age 18 - 50 · All Participants · 5 Total Inclusion Criteria

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