Blood Flow Restriction Exercise for Cardiac Health

EM
Overseen ByEvan Matthews
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Montclair State University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury. Because blood flow in and out of the limbs is decreased, this may have consequences for blood flow through the heart. The purpose of this study will be to test cardiac dynamics during blood flow restriction resistance exercise to determine if cardiac blood flow is impacted. It is hypothesized that both non-BFR exercise and BFR exercise will increase heart rate shortening various cardiac cycle parameters, but BFR exercise will increase the isovolumetric contraction time vs non-BFR exercise due to an increase in total peripheral resistance. It is also hypothesized that BFR exercise will lower early ventricular filling parameters due to lower venous return.

Are You a Good Fit for This Trial?

This trial is for generally healthy individuals interested in how blood flow restriction during low weight resistance exercises affects the heart's blood flow and dynamics.

Inclusion Criteria

I am generally in good health.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo blood flow restriction resistance exercise to test cardiac dynamics

6 weeks
Weekly visits for exercise sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Blood Flow Restriction Resistance Exercise

Trial Overview

The study tests cardiac dynamics by comparing traditional non-BFR (Blood Flow Restriction) exercise to BFR exercise, hypothesizing changes in heart rate and specific aspects of the cardiac cycle due to altered peripheral resistance and venous return.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Intervention groupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Montclair State University

Lead Sponsor

Trials
14
Recruited
1,200+