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Radiotherapy Techniques for Sinonasal Malignancy
This trial will test whether IMRT or proton radiation therapy improves local control rates and lowers toxicity compared to conventional radiation therapy in the treatment of locally advanced sinonasal malignancy.
- Adenoid Cystic Carcinoma
- Squamous Cell Carcinoma
- Sinonasal Cancer
- Sinonasal Carcinoma
- Mucoepidermoid Carcinoma
- Schneiderian Carcinoma
- Myoepithelial Carcinoma
Inclusion CriteriaYou will be eligible if you check “Yes” for the criteria below
Study ObjectivesOutcome measures can provide a clearer picture of what you can expect from a treatment.
Awards & Highlights
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Who is running the clinical trial?
- You are currently addicted to alcohol.You are taking any other experimental medications for a different study.You have had allergic reactions to drugs similar to cisplatin, which is a type of chemotherapy.There is evidence that the cancer has spread to other parts of the body or to the covering of the brain and spinal cord.You have had radiation treatment for tumors in your head, neck, skull base, or brain before.You have had another type of cancer, but it has been treated and you have been cancer-free for at least 2 years. Some specific types of early-stage cancers are allowed within the past 2 years, such as certain types of skin, breast, or cervical cancers.You have been diagnosed with specific types of tumors in certain areas of the head and neck.You are able to perform daily activities without any major limitations or only have minor limitations due to your health condition.Your organs and bone marrow are working normally.You have been diagnosed with specific types of cancer in the nasal and sinus area, as well as certain types of advanced stage tumors. The diagnosis must be confirmed by your treating hospital.
- Group 1: Proton beam therapy
- Group 2: IMRT
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the size of the cohort involved in this research?
"Affirmative, the data hosted on clinicaltrials.gov documents that this medical trial is currently recruiting patients. Initially posted in July 2011 and most recently updated June 2021, the study requires 90 participants to be recruited between two sites."
Is enrollment for this trial still available to interested participants?
"Per the clinicaltrials.gov website, this trial is actively looking for participants to enrol in it; having first been posted on July 1st 2011 and updated as recently as June 2nd 2021."
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