2030 Participants Needed

Natural History Study for Thyroid Cancer

Recruiting at 1 trial location
EG
Overseen ByElizabeth G Grubbs
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial focuses on understanding medullary thyroid cancer, a rare form of thyroid cancer. Researchers observe how this cancer develops and spreads, particularly when it affects other parts of the body. Participants will complete questionnaires about their health, finances, and quality of life, and some will have their blood pressure checked daily. The trial suits individuals with medullary thyroid cancer who are already part of the Medullary Thyroid Cancer Registry, especially if the cancer has advanced.

As an unphased trial, this study provides a unique opportunity for patients to contribute to a deeper understanding of medullary thyroid cancer and its impact.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the clinical team involved in the study.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to gather detailed insights into how medullary thyroid cancer impacts patients' lives, beyond just the medical symptoms. By using regular questionnaires and daily blood pressure measurements, the trial seeks to explore how factors like finances and quality of life affect patients' experiences with the disease. Unlike standard treatments that focus solely on medical intervention, this approach provides a more holistic understanding of the condition, potentially leading to improved management strategies for advanced disease.

Who Is on the Research Team?

EG

Elizabeth G Grubbs

Principal Investigator

M.D. Anderson Cancer Center

Are You a Good Fit for This Trial?

Inclusion Criteria

Aims 1 and 2: A diagnosis of MTC
Aims 1 and 2: A registrant in the Medullary Thyroid Cancer Registry (MTCR). Patients of all disease phases will be eligible for enrollment
Aim 3: A diagnosis of advanced phase (red or gray) MTC as determined by clinical team
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observational

Patients complete questionnaires about health, finances, and quality of life 2-4 times per year

Up to 4 years
2-4 visits per year (virtual)

Monitoring

Patients complete a daily questionnaire and undergo blood pressure measurements

12 weeks
Daily monitoring (self-reported)

Follow-up

Participants are monitored for safety and effectiveness after observational period

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Blood Pressure Measurement
  • Questionnaire Administration

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Observational (questionnaire, blood pressure)Experimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+