Maternal Brain Imaging in Opioid Use Disorder

Overseen By Karlye Pinto, RN

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: Indiana University

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

40 Participants Needed

Trial Summary

What is the purpose of this trial?

This research study aims to learn more about opioid use disorder (OUD) during pregnancy and how outcomes for pregnant women and their newborns can be improved. During pregnancy, people with OUD are prescribed medication-assisted therapy (MAT). The investigators are interested to know how the medication is broken down by the body during pregnancy and how effective it is. The investigators also want to learn if this medication and OUD have any effect on the different parts of the brain when compared to mothers without OUD.

Eligibility Criteria

Inclusion Criteria

You are over 18 years of age.

You are currently taking Buprenorphine.

You are pregnant with a single fetus.

Treatment Details

Participant Groups

Group I: Pregnant Mothers with Opioid Use Disorder Experimental Treatment 4 Interventions

Planned recruitment of 20 mothers with Opioid Use Disorder who are on Buprenorphine at the time of screening.

Group II: Pregnant Mothers Experimental Treatment 2 Interventions

Planned recruitment of 20 mothers who do not have any history of opioid use disorder.

Who Is Running the Clinical Trial?

Indiana University

Lead Sponsor

Trials

1,063

Recruited

1,182,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials

2,658

Recruited

3,409,000+