Broccoli Microgreens for Breast Cancer and Obesity
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether eating broccoli microgreens, young and nutrient-rich broccoli plants, can help obese breast cancer survivors maintain health and reduce the risk of cancer recurrence. Researchers aim to determine if these microgreens improve metabolism and reduce inflammation, both crucial for lowering cancer risk. Participants will consume a cup of these microgreens daily for two weeks to assess adherence to this diet and observe bodily responses. Women who have completed breast cancer treatment, are classified as obese, and have no allergies to broccoli may be suitable for this study. As an unphased trial, this study provides a unique opportunity to contribute to groundbreaking research that could benefit future breast cancer survivors.
Do I need to stop my current medications for this trial?
The trial information does not specify if you need to stop taking your current medications. However, you must avoid cruciferous vegetables during the study and cannot take broccoli extract supplements.
What prior data suggests that broccoli microgreens are safe for human consumption?
Research shows that broccoli microgreens (BMG) are generally well-tolerated. Although clear information on negative effects in humans is lacking, studies with mice have demonstrated benefits for gut health and metabolism. This suggests BMG might be safe and beneficial for humans as well. Since this study is not part of a typical clinical trial, safety information is limited. However, as BMG is a type of food and broccoli is commonly consumed without major safety issues, BMG is likely safe for daily use.12345
Why are researchers excited about this trial?
Unlike standard treatments for breast cancer and obesity, which often involve medications, surgery, or extensive lifestyle changes, the use of broccoli microgreens offers a natural, dietary approach. Researchers are excited about this treatment because broccoli microgreens are rich in sulforaphane, a compound known for its potential anti-cancer and anti-obesity properties. This unique mechanism of action, targeting health at a cellular level through natural compounds, could provide a simpler and more holistic alternative to traditional treatments. Plus, consuming a cup of these microgreens daily is an easy and non-invasive method, potentially making it more accessible and appealing for patients.
What evidence suggests that broccoli microgreens might be an effective treatment for breast cancer and obesity?
Research has shown that broccoli microgreens, rich in nutrients, might help lower cancer risk. Animal studies have found that these microgreens can improve gut health and metabolism, which are crucial for better health in individuals with obesity. Some research suggests that compounds in broccoli microgreens, such as sulforaphane, may help fight cancer. Other studies have found that consuming broccoli-based foods can lower cancer risk. While more human research is needed, these findings suggest that broccoli microgreens could benefit breast cancer survivors dealing with obesity. In this trial, participants will consume one serving of raw broccoli microgreens daily for a 2-week period to evaluate these potential benefits.56789
Who Is on the Research Team?
Yuanyuan (Rose) Li, M.D., Ph.D.
Principal Investigator
University of Maryland
Are You a Good Fit for This Trial?
This trial is for obese breast cancer survivors who are interested in exploring how a diet including broccoli microgreens (BMG) might impact their health and potentially reduce the risk of cancer recurrence. Participants should be willing to consume BMG daily.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume one serving size (one cup, ~57 gram) of raw BMG daily for a 2-week period
Follow-up
Participants are monitored for changes in metabolic parameters and gut microbiome after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Broccoli Microgreen
Trial Overview
The study investigates if eating one cup of broccoli microgreens every day for two weeks can help manage weight, improve metabolism, and reduce inflammation in obese breast cancer survivors. It will measure changes in body fat, glucose levels, lipids, and gut bacteria.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
All participants are in BMG group and will consume one serving size (one cup, \~57 gram) of raw BMG daily for 2-week period of time.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Maryland, Baltimore
Lead Sponsor
University of Maryland, College Park
Collaborator
Citations
Broccoli Microgreen Metabotyping in Obese Breast Cancer ...
This clinical trial is focused on exploring the potential health benefits of broccoli microgreens for obese breast cancer survivors.
Impact of Sulforaphane on Breast Cancer Progression and ...
Another study found that maternal dietary broccoli sprouts (BSps) inhibited and prevented mammary cancer formation and exhibited suppressive ...
Broccoli Microgreens for Breast Cancer and Obesity
Trial Overview The study investigates if eating one cup of broccoli microgreens every day for two weeks can help manage weight, improve metabolism, and reduce ...
Effects of long-term consumption of broccoli sprouts on ...
Most of these reported effects are linked to anti-cancer properties and epidemiological studies have evidenced a decrease in the risk of cancer with the intake ...
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aacrjournals.org
aacrjournals.org/cancerpreventionresearch/article/11/8/451/47182/Temporal-Efficacy-of-a-Sulforaphane-Based-BroccoliTemporal Efficacy of a Sulforaphane-Based Broccoli Sprout ...
Our study indicates a prenatal/maternal BSp dietary treatment exhibited maximal preventive effects in inhibiting breast cancer development.
Metabotyping of Broccoli Microgreen in Obese Breast ...
Broccoli microgreens (BMG) are young broccoli plants packed with nutrients, and research suggests they may help prevent cancer.
Broccoli Consumption and Risk of Cancer - PubMed Central
Background: The scientific literature has reported an inverse association between broccoli consumption and the risk of suffering from several types of cancer; ...
Broccoli Microgreens Nutrition: Everything You Need To ...
Another study[8] has shown that eating broccoli microgreens inhibits breast cancer stems cells. The polyphenols and glucosinolates in broccoli ...
Metabotyping of Broccoli Microgreen in Obese Breast ...
Broccoli microgreens (BMG) are young broccoli plants packed with nutrients, and research suggests they may help prevent cancer. Previous studies in mice showed ...
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