40 Participants NeededMy employer runs this trial

Exercise for Obesity

KD
BM
Overseen ByBlake Metcalf, DCN
Age: 18 - 65
Sex: Any
Trial Phase: Phase 2
Sponsor: Arkansas Colleges of Health Education
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss.

Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.

Are You a Good Fit for This Trial?

Inclusion Criteria

BMI 25-45
Healthy enough to exercise
I am between 18 and 59 years old.

Exclusion Criteria

I am taking medicines or supplements that affect my energy levels.
Currently exercising more than once per week
Currently dieting for weight loss
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo a 16-week supervised aerobic exercise intervention, either in a fasted state or post-prandially

16 weeks
4 visits per week (in-person)

Follow-up

Participants are monitored for changes in body composition, metabolic rate, and hormonal responses

9 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Fasted vs. Fed State Exercise

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Fed exercise groupExperimental Treatment1 Intervention
Group II: Fasted groupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Arkansas Colleges of Health Education

Lead Sponsor

Trials
7
Recruited
1,200+