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Surgical Resection for Brain Cancer

N/A
Recruiting
Led By Elizabeth Maher, MD, PhD
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Male or female, any age and any racial or ethnic group
Karnofsky Performance status > 70%
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at end of follow-up period- between days 1-14
Awards & highlights

Study Summary

This trial is designed to study the correlation between the metabolic phenotype of a brain tumor and the tumor's histopathological diagnosis. The trial will also study the correlation between the metabolic phenotype and the patient's response to treatment and overall survival.

Who is the study for?
This trial is for individuals of any age with a brain tumor, who can consent to the study or have a guardian who can. They must not be pregnant, should be in relatively good health (Karnofsky Performance status > 70%), and able to undergo MRI scans unless they have certain medical devices or severe claustrophobia.Check my eligibility
What is being tested?
The trial involves surgical removal of the brain tumor while also studying its metabolism using a special form of glucose during surgery. The metabolic profile will be compared with high-resolution imaging before surgery and molecular analysis after, aiming to better understand the tumor's characteristics.See study design
What are the potential side effects?
Since this study focuses on observation rather than treatment, side effects are primarily related to standard risks associated with surgical resection of brain tumors which may include bleeding, infection, neurological deficits depending on the tumor location.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My gender, age, and ethnicity do not limit my eligibility.
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I am mostly independent and can care for myself.
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I am not pregnant and cannot become pregnant due to surgery, menopause, or I use two forms of birth control.
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My brain scans suggest a tumor or I've had a biopsy confirming a tumor before planned surgery.
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I speak Spanish.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at end of follow-up period- between days 1-14
This trial's timeline: 3 weeks for screening, Varies for treatment, and at end of follow-up period- between days 1-14 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
metabolic phenotype correlation to clinical endpoints
Secondary outcome measures
baseline imaging data review
molecular profiling

Trial Design

1Treatment groups
Experimental Treatment
Group I: surgical resection of a brain tumorExperimental Treatment1 Intervention
The patient will undergo surgical removal of the tumor after infusion of 13C-glucose using standard neurosurgical technique, including frameless stereotaxy for surgical navigation, and microsurgical technique. --------------------------------------------------------------------------------

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,043 Previous Clinical Trials
1,053,510 Total Patients Enrolled
Elizabeth Maher, MD, PhDPrincipal Investigator - University of Texas
Children's Medical Center of Dallas, The University of Texas Southwestern Medical Center At Dallas, UT Southwestern Medical Center-Zale Lipshy Campus
Mc Gill University (Medical School)
Brigham & Women'S Hospital (Residency)
1 Previous Clinical Trials

Media Library

Surgical Resection (Other) Clinical Trial Eligibility Overview. Trial Name: NCT01668082 — N/A
Brain Tumor Research Study Groups: surgical resection of a brain tumor
Brain Tumor Clinical Trial 2023: Surgical Resection Highlights & Side Effects. Trial Name: NCT01668082 — N/A
Surgical Resection (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01668082 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies available for participants of this experiment?

"Affirmative. The clinicaltrials.gov webpage proclaims that this research endeavour, which was initially advertised on August 1st 2009, is still recruiting volunteers for their trial. Currently, the team requires 40 individuals to participate at a single site."

Answered by AI

How many participants has this clinical trial recruited so far?

"Yes, the information hosted on clinicaltrials.gov affirms that this medical study is actively recruiting participants. The trial was first introduced to the public on August 1st 2009 and has since been updated as recently as March 30th 2022; it seeks 40 patients from a single location."

Answered by AI
~4 spots leftby Feb 2026