SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury

Overseen By Charles Mikell, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Stony Brook University

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

200 Participants Needed

Trial Summary

What is the purpose of this trial?

Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models. In this study, we will use a novel technique, "SeeMe," to objectively assess the level of consciousness in patients suffering from comas following ABI. SeeMe is a program that quantifies total facial motion over time and compares the response after a spoken command (i.e. "open your eyes") to a pre-stimulus baseline.

Research Team

Sima Mofakham, PhD

Principal Investigator

Stony Brook Medicine

Eligibility Criteria

Inclusion Criteria

You must be 18 years of age or older.

You are comatose due to an acute brain injury such as traumatic brain injury, spontaneous subarachnoid hemorrhage, or severe meningoencephalitis and have a Glasgow Coma Score of less than 9.

You are a healthy volunteer.

Treatment Details

Participant Groups

Group I: Control Experimental Treatment 2 Interventions

Healthy subjects will undergo SeeMe and CRS-R assessment once.

Group II: Acute Brain Injury (ABI) Experimental Treatment 2 Interventions

Patients that have suffered an ABI resulting in Coma (Glasgow Coma Scale (GCS) \< 9) will undergo SeeMe and CRS-R assessment once a day until hospital discharge

Who Is Running the Clinical Trial?

Stony Brook University

Lead Sponsor

Trials

225

Recruited

41,700+