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Cognitive Reappraisal Training for Borderline Personality Disorder (BPD Trial)
BPD Trial Summary
This trial will test a new clinical intervention for patients with Borderline Personality Disorder. The intervention is training in reappraisal-by-distancing, which is hypothesized to improve neural and behavioral targets. If successful, this intervention has the potential to improve clinical outcomes for patients with BPD.
BPD Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.BPD Trial Design
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Who is running the clinical trial?
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- You have been diagnosed with Schizotypal Personality Disorder or Avoidant Personality Disorder. This is because people with these disorders may affect the accuracy of the study results.I am healthy, have Borderline Personality Disorder, and can consent to treatment.I am healthy, have Borderline Personality Disorder, and can consent to treatment.I am older than 55.
- Group 1: Cognitive Reappraisal-by-Distancing (CRD)
- Group 2: Control Downregulate Condition (CD)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: You will receive the treatment for 3 null
- Follow Ups: You may be asked to continue sharing information regarding the trial for 3 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the research project currently seeking participants?
"Indeed, the information accessible on clinicaltrials.gov claims that this medical trial is presently recruiting volunteers. The study was initially posted on November 30th 2021 and has been recently amended as of July 7th 2022. A total of 228 individuals are required at a single clinical centre for enrollment in the trial to be completed."
Is participation in this trial limited to individuals of a certain age bracket?
"The investigators for this trial have specified that only those aged 18 to 55 can be enrolled. For younger and elderly participants, there are 6 separate studies available for their consideration."
Who is the optimal participant for this clinical research?
"This trial is enrolling 228 suitable participants aged 18 - 55 diagnosed with Borderline personality disorder. To qualify, applicants must be medically sound and mentally capable of giving informed consent in written form."
What are the primary goals that this trial is aiming to accomplish?
"This medical trial's primary outcome is the Change in Zanarini Rating Scale for Borderline Personality (ZAN-BPD). Secondary outcomes are the Difficulty in Emotion Regulation Scale Scores (DERS) from 6 to 216, Beck Depression Inventory Score 0-63, and State-Trait Anxiety Inventory score 20 - 80. All of these metrics will be assessed at Baseline and up to 6 weeks into treatment."
To what extent is the public participating in this experiment?
"Correct. Documentation on clinicaltrials.gov attests to this experiment being currently open for recruitment, with the initial posting date of November 30th 2021 and last update dated July 7th 2022. The study is aiming to enroll 228 participants from a single location."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- Icahn School of Medicine at Mount Sinai: < 48 hours
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