Smart Watch for Bone Cancer

Overseen By Zachary Burke, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Case Comprehensive Cancer Center

Disqualifiers: Under 18, No smartphone, Tattoos, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how a smartwatch can track changes in walking stability and daily activities during cancer treatment. The researchers aim to determine if the smartwatch can detect these changes and assist in creating personalized monitoring tools for patients. The trial includes different groups, such as those receiving radiation or surgery for bone cancer. It suits individuals with primary osteosarcoma or metastatic bone disease in the legs or pelvis who are considering surgery or radiation and can wear a smartwatch for most of the day. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance personalized care for future patients.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this smartwatch is safe for patients with bone cancer?

Research shows that smartwatches are generally safe and easy for patients to use. Studies have found that these devices can help track health issues like heart problems and movement disorders. They can even detect early signs of illnesses such as COVID-19.

For cancer patients, wearable devices like smartwatches have successfully monitored activity levels, potentially improving overall activity during treatment. The side effects of using smartwatches are minimal, making them a safe choice for monitoring health in bone cancer patients.

Overall, smartwatches do not pose major safety risks and are considered reliable for use in medical settings. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Smart Watch for bone cancer because it represents a novel approach in managing the disease. Unlike traditional treatments like chemotherapy, radiation, or surgery, which directly target cancer cells, the Smart Watch is designed to monitor patients' conditions in real-time, potentially catching complications early. This non-invasive method could lead to more personalized and timely interventions, enhancing the quality of life for patients. Additionally, the use of wearable technology offers a convenient and continuous way to track health metrics, setting it apart from current standard care options that often require frequent hospital visits.

What evidence suggests that this smartwatch is effective for monitoring treatment response in bone cancer patients?

Research has shown that smart watches can effectively track bodily changes, particularly for individuals with bone conditions. Smart watches equipped with special sensors can monitor these changes and help identify issues early. Studies have found that the artificial intelligence (AI) in these devices accurately detects bone problems, which is crucial for planning treatment and predicting outcomes. This trial will explore the use of smart watches in various contexts, including for patients receiving palliative radiation or prophylactic surgery for metastatic bone disease, as well as for sarcoma patients. While no direct evidence suggests that a smart watch can cure bone cancer, it appears promising in supporting treatment by monitoring the body's response. ^{2 6 7 8 9}

Are You a Good Fit for This Trial?

This trial is for patients with primary osteosarcoma or metastatic bone disease. Participants should be able to wear a smartwatch for at least 12 hours daily, use a mobile app, and complete weekly questionnaires. Specific inclusion and exclusion criteria are not provided.

Inclusion Criteria

I am mostly able to care for myself and carry out normal activities.

I am being considered for surgery or a radiology procedure.

My cancer is in the bones of my legs or pelvis.

Exclusion Criteria

I am younger than 18 years old.

No access to a smartphone (iOS or Android) to interface with watch application

Tattoos located on the skin of the wrist or forearm where the watch will be placed or other skin conditions preventing adequate sensor function

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive palliative radiation or prophylactic surgery, and are monitored using smartwatches and mobile applications to collect actigraphy data and ePRO evaluations

12 weeks

Continuous monitoring with smartwatches

Follow-up

Participants are monitored for adherence and effectiveness of the wearable technology in capturing recovery and complications

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Smart Watch

Trial Overview The study tests if a smartwatch can monitor changes in walking stability and daily activity performance during cancer treatment. It aims to create tools that track treatment response and predict complications while evaluating the practicality of using such technology.

How Is the Trial Designed?

Group I: prophylactic surgery for metastatic bone disease patients Experimental Treatment 1 Intervention

Group II: Sarcoma patients Experimental Treatment 1 Intervention

Group III: Palliative radiation for metastatic bone disease patients Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Case Comprehensive Cancer Center

Lead Sponsor

Trials

472

Recruited

33,400+

Citations

1. withpower.com withpower.com/trial/phase-bone-diseases-7-2025-4bb5e

Smart Watch for Bone Cancer · Info for Participants ... Smart Watch will have tolerable side effects & efficacy for patients with Bone Disease, Osteosarcoma, Bone Cancer and Osteosarcoma. Learn more about the study.

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11311270/

Artificial Intelligence in Detection, Management, and ... AI applications in CT for bone metastasis provide substantial potential benefits such as great diagnostic accuracy, efficient segmentation of ...

3. ajcn.nutrition.org ajcn.nutrition.org/article/S0002-9165(23)03666-3/fulltext

Next-generation smart watches to estimate whole-body ... This study evaluated smart watches with integrated bioelectrical impedance analysis (BIA) sensors for their ability to measure and monitor changes in body ...

4. taiwan-healthcare.org taiwan-healthcare.org/en/edm-detail?id=0slwkaqpx2y6io8v

AI Revolution in Bone Diagnostics: Decode Bone Health ... This tool assists healthcare professionals in assessing patients' BMD risk, providing advices for referrals or further medical action.

5. bmccancer.biomedcentral.com bmccancer.biomedcentral.com/articles/10.1186/s12885-025-13631-0

Accuracy of artificial intelligence in detecting tumor bone ... Accurate early BM diagnosis shows high importance in effective tumor staging, treatment planning, and prognosis assessment, placing a high ...

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10994271/

The Use of Wearable Devices in Oncology Patients This article summarizes the current literature on wearable technologies in oncology patients for the purpose of prognostication, treatment monitoring, and ...

7. sciencedirect.com sciencedirect.com/science/article/pii/S2095254621000909

Review Effect and feasibility of wearable physical activity ... Our findings show that interventions using physical activity trackers and pedometers are effective at improving physical activity levels following a cancer ...

8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10625201/

Smartwatches in healthcare medicine - PubMed Central - NIH Smartwatches have shown promise in detecting heart diseases, movement disorders, and even early signs of COVID-19.

9. medanta.org medanta.org/patient-education-blog/how-wearable-devices-help-in-early-detection-of-health-issues

How Wearable Devices Help in Early Detection of Health ... Medical-grade devices give more reliable results than consumer wearables. Is my health data from wearables secure? Security remains a valid ...