24 Participants Needed

Ellacor Micro-Coring for Wound Care

Recruiting at 1 trial location
KV
DM
Overseen ByDelia Medical Science Liaison, PharmD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how different skin care products aid recovery after using Ellacor® Micro-coring®, a treatment for moderate to severe facial wrinkles. Participants will follow one of five skin care routines, each using a combination of products like creams and bandages, to determine which is most effective. Ideal candidates have noticeable wrinkles on their mid and lower face and have not undergone recent facial surgeries or treatments. As an unphased trial, this study allows participants to contribute to innovative skin care research and identify the most effective post-treatment routine.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on high doses of blood thinners or certain other treatments like chemotherapy or high-dose corticosteroids. It's best to discuss your specific medications with the trial team.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that the Ellacor Micro-Coring procedure is safe when used correctly. Studies have found it is well-tolerated on skin at levels up to 10% density and a depth of up to 4mm. This indicates that, when applied properly, the procedure is unlikely to cause harm. However, it should not be used on skin with conditions like tumors or keloids, as it may not be safe in those cases.

For the specific post-care products tested with Ellacor, direct safety data is not available. However, the trial's "Not Applicable" phase suggests these skincare products are likely considered low-risk, as they focus on recovery after the main procedure rather than introducing new, untested treatments.12345

Why are researchers excited about this trial?

Researchers are excited about the Ellacor® Micro-coring® technique for wound care because it offers a novel approach to skin regeneration. Unlike traditional wound care treatments that often rely on topical applications to promote healing, this technique physically removes tiny columns of skin to stimulate natural healing processes. This method could potentially lead to faster recovery times and improved skin texture as the skin regenerates. Additionally, combining this innovative technique with products like Regenerating Skin Nectar or Ariessence PDGF solution might enhance the healing process, offering new hope for more effective wound care.

What evidence suggests that this trial's treatments could be effective for wound care?

Research shows that Ellacor Micro-coring can enhance skin appearance. One study found that 91% of participants experienced improvement in moderate to severe wrinkles within six months. This method uses tiny needles to remove small bits of skin, tightening and smoothing the skin. Many notice changes after just one treatment, and their skin feels refreshed and rejuvenated after several sessions. These findings suggest that Ellacor Micro-coring effectively improves skin texture and reduces wrinkles.

In this trial, participants will receive various post-procedure treatments to assess their effectiveness in wound care. These treatments include Regenerating Skin Nectar with Tegaderm, Ariessence PDGF solution with Kerra+ Recovery Cream and Tegaderm, Tegaderm only, Kerra+ Recovery Cream with Tegaderm, and Ariessence PDGF solution with Alastin and Tegaderm.36789

Are You a Good Fit for This Trial?

This trial is for individuals who have undergone skin treatments using Ellacor Micro-Coring Technology. Participants should be following specific post-procedural care regimens, but the exact eligibility criteria are not provided in the given information.

Inclusion Criteria

Willingness to sign Informed Consent Form
Fitzpatrick Skin Type I to IV
Have moderate to severe wrinkles on the mid and lower face, according to Lemperle Wrinkle Severity Scale (LWSS), i.e. score 3, 4 or 5
See 1 more

Exclusion Criteria

I have not had facial plastic surgery or scars less than 12 months old.
I have not had injections or skin treatments in the area for the last 6 months.
I am not willing to avoid cosmetic treatments during the study.
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive post-procedure skin care regimens with various products including Tegaderm, Alastin, Kerra+, and PDGF

90 days
4 visits (in-person) on Day 0, Day 7, Day 30, and Day 90

Follow-up

Participants are monitored for safety and effectiveness after treatment, including GAIS assessment and clinical assessments

90 days
4 visits (in-person) on Day 0, Day 7, Day 30, and Day 90

What Are the Treatments Tested in This Trial?

Interventions

  • Ellacor® Micro-coring®

Trial Overview

The study investigates the safety and effectiveness of different post-care products used in five distinct skin care routines after treatment with Ellacor Micro-Coring Technology, which has been available in the U.S. since 2021.

How Is the Trial Designed?

5

Treatment groups

Active Control

Group I: Regenerating Skin Nectar (by Alastin) + TegadermActive Control1 Intervention
Group II: Ariessence PDGF solution + Kerra+ Recovery Cream + TegadermActive Control1 Intervention
Group III: Tegaderm OnlyActive Control1 Intervention
Group IV: Kerra+ Recovery Cream (by Quthero) + TegadermActive Control1 Intervention
Group V: Ariessence Platelet-Derived Growth Factor (PDGF) solution +Alastin + TegadermActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Cytrellis Biosystems, Inc.

Lead Sponsor

Trials
7
Recruited
180+

Citations

Safety and Efficacy of Ellacor® Micro-coring® Following ...

Safety and Efficacy of Ellacor® Micro-coring® Following Best Practices on Technique and Post-Procedural Care. ClinicalTrials.gov ID NCT07260578.

Micro-Coring® Procedure

Ellacor uses hollow needles to remove micro-cores of skin, resulting in an improved appearance of moderate and severe wrinkles in the mid and lower face.

Histologic Study of Abdominal Skin Treated With Mechanical ...

Mechanical Dermal Micro‐Coring Technology (MCT; Ellacor System) achieves skin tightening and wrinkle reduction through direct mechanical ...

Effectiveness of Ellacor Treatment and When to See ...

Clinical studies paint a compelling picture of Ellacor's success. One such study reported a 91% improvement in moderate to severe wrinkles within six months of ...

Patient Results | ellacor®

I noticed a change in my skin after just one treatment, and after my third session, I felt like my skin was just so refreshed and brought back to life. Ellacor ...

Safety and Efficacy of Ellacor® Micro-coring® Following ...

Safety and Efficacy of Ellacor® Micro-coring® Following Best Practices on Technique and Post-Procedural Care. ClinicalTrials.gov ID NCT07260578.

October 30, 2025 Cytrellis Biosystems, Inc. Robert Hinz Vice ...

The results of this study establish the safety of the ellacor Micro-. Coring procedure at densities up to 10% and at a depth of up to 4mm, ...

Privacy Policy

The ellacor® procedure should not be used for the treatment of areas of skin with dermatosis (e.g. skin tumors, keloids or in case of predisposition to keloids, ...

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ellacor.com

ellacor.com/

Ellacor® System with Micro-Coring® Technology

The ellacor® procedure should not be used for the treatment of areas of skin with dermatosis (e.g. skin tumors, keloids or in case of predisposition to keloids, ...