1000 Participants Needed

Psychophysics for Behavior

TE
Overseen ByTahra Eissa
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Colorado, Boulder
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The investigators will record behavioral responses from human participants on crowdsourcing platform Prolific to identify the decision strategies humans apply short-term, long-term, and multi timescale (across both timescales) inference tasks. Participants will perform a Jar Switching Task (described in Research Strategy Aim 1- "Jar Switching Task") in which balls are drawn with replacement from one of two known jars. The current jar in use switches based on an underlying change rate across trials. Subjects must perform three task blocks: 1) report the current jar in use (short-term inference), 2) predict the subsequent jar (long-term inference), and 3) both report and predict the jars (multi-timescale inference). The investigators will record these responses, the number (and sequence) of balls drawn, and the response time (time from the end of trial until the response) for each trial. Subjects will perform all blocks (parameters and number of blocks to be determined by inference model development and testing prior to task development) so that we can compare responses at each timescale. Since participants participate voluntarily for small sums of money (around $10/ hour based on duration of task) and the investigators' previous studies have collected over 200 subjects in a matter of days, they will aim to record behavioral data from 1000 subjects. This number allows them to address the broad range of subject variability expected using Bayesian statistical methods such as Bayes factors.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Psychophysics for Behavior?

The research highlights the use of measurement feedback systems (MFSs) and systematic client feedback as effective tools in improving treatment outcomes in mental health. These methods help therapists monitor patient progress and adjust treatments accordingly, which can enhance the effectiveness of behavioral interventions like Psychophysics.12345

Is there any safety data available for the treatment Psychophysics for Behavior?

The available research does not provide specific safety data for the treatment Psychophysics for Behavior. However, general safety practices in clinical trials, such as tracking adverse events (unwanted effects from treatment), are discussed, which are important for ensuring participant safety in any trial.678910

How does the treatment in the Psychophysics for Behavior trial differ from other treatments?

This treatment is unique because it uses psychophysics, which is the study of how physical stimuli affect behavior, to assess and potentially treat conditions. Unlike traditional treatments that might focus on medication or direct physical interventions, this approach involves measuring and analyzing sensory perceptions and responses to stimuli, which can provide insights into both sensory and cognitive functions.1112131415

Research Team

TE

Tahra Eissa

Principal Investigator

University of Colorado, Boulder

Eligibility Criteria

This trial is for adults in the US who use Prolific, have a high approval rating (95%), and score at least 80% on a pre-test. Participants should speak fluent English.

Inclusion Criteria

Adult Prolific participants who have a 95% approval rating and achieve a minimum score of 80% on our pre-test
Participants must speak fluent English
Participants must be in the US

Exclusion Criteria

Not applicable.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1 week

Task Performance

Participants perform the Jar Switching Task involving short-term, long-term, and multi-timescale inference tasks

30 minutes per session
1 session (online)

Data Analysis

Behavioral data from participants is analyzed using Bayesian statistical methods

2 weeks

Follow-up

Participants are monitored for any additional feedback or data collection post-task

1 week

Treatment Details

Interventions

  • Psychophysics
Trial Overview The study tests how people make decisions using an online Jar Switching Task. It measures short-term, long-term, and multi-timescale inference by asking participants to identify patterns in which jar is being used to draw balls over several trials.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Environmental Feature ExperimentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Colorado, Boulder

Lead Sponsor

Trials
128
Recruited
29,600+

University of Pennsylvania

Collaborator

Trials
2,118
Recruited
45,270,000+

University of Houston

Collaborator

Trials
155
Recruited
48,600+

Findings from Research

Using outcome measures in psychotherapy can significantly improve treatment results, especially for patients who are likely to struggle with negative outcomes.
A meta-analysis indicates that monitoring patient feedback and providing clinicians with decision-making tools can enhance treatment effectiveness for those showing early signs of treatment failure.
Outcome measures for practice.Whipple, JL., Lambert, MJ.[2015]
Systematic client feedback, such as the Partners for Change Outcome Management System (PCOMS), can improve psychotherapy outcomes by addressing issues like client dropouts and varying therapist effectiveness, as supported by randomized clinical trials.
PCOMS not only provides psychometric measures but also emphasizes the importance of client perspectives in therapy, potentially shifting the focus from a purely medical model to a more relational and scientific approach in psychotherapy practice.
The Partners for Change Outcome Management System (PCOMS) revisiting the client's frame of reference.Duncan, BL., Reese, RJ.[2019]
In the ICON8 ovarian cancer clinical trial, 51,019 adverse events were reported, but only 61% of serious adverse events were matched to existing adverse events, indicating a significant gap in safety reporting.
Re-analyzing safety data by including serious adverse events increased the detection of grade 3 or worse safety events, highlighting the importance of comprehensive safety data collection for accurate risk assessment in clinical trials.
Overlap between adverse events (AEs) and serious adverse events (SAEs): a case study of a phase III cancer clinical trial.James, EC., Dunn, D., Cook, AD., et al.[2021]

References

Bridging the gap between best evidence and best practice in mental health. [2022]
Outcome measures for practice. [2015]
The Partners for Change Outcome Management System (PCOMS) revisiting the client's frame of reference. [2019]
The Technology of Measurement Feedback Systems. [2021]
Progress in health-related behavioral intervention research: Making it, measuring it, and meaning it. [2022]
10th annual meeting of the Safety Pharmacology Society: an overview. [2018]
Overlap between adverse events (AEs) and serious adverse events (SAEs): a case study of a phase III cancer clinical trial. [2021]
The impact of minor adverse event tracking on subject safety: a web-based system. [2009]
Comparing the Value of Data Visualization Methods for Communicating Harms in Clinical Trials. [2022]
10.United Statespubmed.ncbi.nlm.nih.gov
Comparison of increasingly detailed elicitation methods for the assessment of adverse events in pediatric psychopharmacology. [2007]
11.United Statespubmed.ncbi.nlm.nih.gov
The place of human psychophysics in modern neuroscience. [2015]
[Application of psychophysics to neurology]. [2008]
13.United Statespubmed.ncbi.nlm.nih.gov
Psychophysical assessment of visual dysfunction. [2018]
Quantitative sensory assessment in toxicology and occupational medicine: applications, theory, and critical appraisal. [2019]
The Psychophysics Toolbox. [2022]
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