Diagnostic Tests for Detecting Barrett's Esophagus
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but if you are on anti-coagulant drugs that cannot be temporarily stopped, you may not be eligible to participate.
Is the diagnostic test for Barrett's Esophagus safe?
How is the EsoCheck/EsoGuard treatment different from other treatments for Barrett's Esophagus?
What is the purpose of this trial?
The purpose of this study is to develop a method to detect Barrett's esophagus (BE) in individuals with a new office-based diagnostic test.
Research Team
Amitabh Chak, MD
Principal Investigator
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Eligibility Criteria
This trial is for individuals over 50 with no chronic GERD, who have two risk factors for Barrett's Esophagus such as being white, having central obesity, male gender, smoking history or a family history of the condition. They must not have swallowing difficulties or blood clotting issues.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Diagnostic Testing
Participants complete a study questionnaire and undergo the EsoCheck/EsoGuard procedure to detect Barrett's esophagus
Endoscopy
Participants with positive EsoGuard results undergo standard of care upper endoscopy; selected negative participants may also undergo research EGD
Follow-up
Participants are monitored for safety and effectiveness after diagnostic procedures
Treatment Details
Interventions
- EsoCheck/EsoGuard (EC/EG)
- Esophago-gastro-duodenoscopy (EGD)
EsoCheck/EsoGuard (EC/EG) is already approved in United States for the following indications:
- Detection of Barrett's Esophagus
- Esophageal Precancer Screening
Find a Clinic Near You
Who Is Running the Clinical Trial?
Case Comprehensive Cancer Center
Lead Sponsor