Personalized Medication for ADHD

Overseen By William Brinkman, MD, MEd, MSc

Age: < 18

Sex: Any

Trial Phase: Academic

Sponsor: Children's Hospital Medical Center, Cincinnati

Must be taking: Stimulants

Disqualifiers: No internet access, No texting

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

Duration: 4-12 weeks

30 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The primary goal of the project is to test personalized medication experiments to inform decisions about future medication use. Our central hypothesis is that our intervention will lead to within subject increases in adolescent involvement in decision making and decreases in uncertainty about future medication use. The investigators view this open label trial as a pilot study to test the feasibility, acceptability, and preliminary efficacy of the medication experiment intervention and therefore warrants further testing in a future larger trial.

Who Is on the Research Team?

William Brinkman, MD, MEd, MSc

Principal Investigator

Cincinnati Children's

Are You a Good Fit for This Trial?

This trial is for adolescents with ADHD who are interested in exploring how personalized medication can affect their condition. It's a pilot study, meaning it's an early test to see if the approach works and is accepted by participants.

Inclusion Criteria

I am a teenager and I have agreed in writing to join the study.

Uncertainty about continued ADHD medication use

A parent or legal guardian must provide written informed consent

Exclusion Criteria

Do not have reliable access to the internet at their home or another location

Will not permit their child to access the internet for study related activities

Are not able or willing to send or receive text messages.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

1 visit (in-person)

Treatment

Participants choose one of five medication experiments to complete and track effects

4-12 weeks

1 visit (in-person)

Follow-up

Participants complete a follow-up study visit to review results and discuss feasibility

3 months

1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

• Personalized ADHD Medication Experiment

Trial Overview The study tests a new way of using ADHD medication tailored to each individual. The goal is to involve teens more in decision-making about their treatment and reduce uncertainty regarding future medication use.

How Is the Trial Designed?

Group I: Intervention Experimental Treatment 1 Intervention

All will choose one of five medication experiment options to complete.

Who Is Running the Clinical Trial?

Children's Hospital Medical Center, Cincinnati

Lead Sponsor

Trials

844

Recruited

6,566,000+