Avoiding Coffee for Atrial Fibrillation
(DECAF Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Given both the increasing population impact of atrial fibrillation (AF) and the widespread consumption of coffee in society, determining an associated benefit or risk of coffee consumption on AF is of great clinical relevance. This study will evaluate the effect of randomly assigning participants undergoing cardioversion to coffee abstinence or coffee continuation over a 6 month period. This study will provide the first, randomized evaluation of coffee on AF outcomes and will provide important information on whether or not coffee has any effect on AF recurrence.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It mainly focuses on coffee consumption, so it's best to discuss your medications with the study team.
Is avoiding coffee safe for humans?
How does avoiding or consuming coffee affect atrial fibrillation compared to other treatments?
This treatment is unique because it focuses on the impact of coffee consumption, which is a common dietary habit, rather than using medication or medical procedures. The research suggests that moderate coffee consumption might be associated with a lower risk of atrial fibrillation, but findings are inconsistent, making this approach different from standard medical treatments.12346
What data supports the effectiveness of the treatment 'Avoid coffee, Consume coffee' for atrial fibrillation?
Who Is on the Research Team?
Gregory M Marcus, MD, MAS
Principal Investigator
University of California, San Francisco
Christopher X Wong, MBBS, PhD
Principal Investigator
University of Adelaide
Christopher C Cheung, MD, MPH
Principal Investigator
Sunnybrook Health Sciences Centre
Are You a Good Fit for This Trial?
This trial is for men and women over 21 who have atrial fibrillation, drink coffee daily, and are scheduled for electrical cardioversion. They must be willing to either abstain from or continue drinking coffee and attend follow-up calls. Exclusions include allergies to coffee, recent heart surgeries, pregnancy plans within six months, or participation in conflicting studies.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomly assigned to either abstain from coffee or continue coffee consumption for up to 6 months
Follow-up
Participants are monitored for safety and effectiveness after treatment, focusing on AF recurrence and other arrhythmias
What Are the Treatments Tested in This Trial?
Interventions
- Avoid coffee
- Consume coffee
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor