Results from a recent paper, the mean age of our patient population was 62.6 years, and the mean ejection fraction was 59.7% (male: 57.4%, female: 60.4%). Mean LA diameter was 38.1 mm. The left atrium (LA) was larger in females than in males (P = 0.026) (48.9 vs. 42.1 mm, respectively). In patients with AF, the mean LA diameter was larger than in the control group (P = 0.004). In addition, the LA volume in men was higher (P = 0.004) than in women (P = 0.045).
Patients with AF are more likely to be elderly. They have higher rates of diabetes and hypertension compared to those with SR. Most AF patients were treated with anti-arrhythmic agents, but those with chronic AF less often received β-blockers. AF is frequently treated with a combination of medical and surgical approaches but this depends on the severity of symptoms and lifestyle of individual patients.
It is crucial to know the main symptom of AF (irregular heart beat) and the associated risk factors when diagnosing AF. In conjunction to electrocardiography, clinical information of AF is of extreme utility in assessing the most serious risk of AF.
Data from a recent study suggest that atrial fibrillation is relatively common, occurring in approximately 1 in 500 adults. In contrast, AF was comparatively rare among older patients. Data from a recent study suggest that AF represents a new public health issue. Identifying risk factors, modifying lifestyle and medication strategies, and implementing effective systems of management may help reduce the burden of AF in the future.
AF is a debilitating disease as well as a major health problem. Given the many options available and advances in cardioversion and catheter ablation, long-term AF termination is a possible goal for the future. There is a long-standing and compelling need for high quality data to guide this endeavor.
Atrial fibrillation is the most common arrhythmia in adults. Its incidence rises exponentially with age and is much higher in males than females. Cardiac factors account for only a minority of cases. The cause of atrial fibrillation is not entirely determined. It is well known that viral infections (parvovirus B19 and human parvovirus B19) can cause heart block and cardiac arrhythmia by activating the parasympathetic nervous system.
AF may run in families. Results from a recent clinical trial suggests that atrial fibrillation is under-diagnosed in families with a history of AF. The higher risk for AF in couples may result in earlier diagnosis of AF in those affected and more effective management.
We present data indicating that kidney denervation can be achieved with minimal complications in selected patients and that these complications can be reversed. The presence of renal impairment may be a determinant of nonresponse after renal-denervation therapy, highlighting the need for further research.
Renal denervation in rabbits significantly reduces the generation of atrial fibrillation in a manner similar to how it reduces AF in humans. Further study of the effects of renal denervation in humans with AF is warranted.
RDN was significantly associated with a reduced risk of death in patients with heart failure. Recent findings support the use of RDN as the treatment of choice for heart failure.
This proof-of-concept study in a real-world population suggests that RDN may improve HRQOL in those with AF. As this study was uncontrolled, we recommend it be performed under a randomised protocol before any clinical trials. These data suggest that RDN is potentially a viable option for HRQOL improvement for AF.
There have not been any new medications approved for the treatment of symptomatic or asymptomatic atrial fibrillation, and no specific biomarkers have been developed for this patient population. Continued studies into biomarkers of the condition are needed to identify individuals with a high likelihood for developing the condition who require more urgent treatment, and to identify those who may respond to newer therapeutic strategies.