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Vitamin

Folic Acid for Arsenic Poisoning

N/A

Waitlist Available

Led By Kevin G Dsouza, MD

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

Study Summary

This trial tests if folic acid can help people exposed to arsenic in Alabama.

Who is the study for?

This trial is for adults over 18 living in a specific area in Birmingham, Alabama with chronic arsenic exposure. Participants must be generally healthy without major health changes in the last month and not currently taking folic acid supplements or have conditions like megaloblastic anemia or malabsorptive syndromes.Check my eligibility

What is being tested?

The study is testing if taking folic acid can help reduce the effects of long-term arsenic poisoning compared to a placebo (a pill with no active ingredient). People will randomly receive either folic acid or placebo to see which works better.See study design

What are the potential side effects?

Folic acid is usually safe but can sometimes cause mild side effects like nausea, loss of appetite, bloating, sleep disturbances, depression, and could rarely trigger allergic reactions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Measurement of urine and blood arsenic metabolites

Secondary outcome measures

Pooled Cohort Probability Score

Respiratory Symptom Questionnaire

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Folic AcidExperimental Treatment1 Intervention

Folic acid 800 ug/day 12 weeks

Group II: PlaceboPlacebo Group1 Intervention

Placebo daily 12 weeks

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Folic Acid

2008

Completed Phase 4

~7610

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,583 Previous Clinical Trials

2,279,944 Total Patients Enrolled

Kevin G Dsouza, MDPrincipal InvestigatorUniversity of Alabama at Birmingham

Media Library

Folic Acid (Vitamin) Clinical Trial Eligibility Overview. Trial Name: NCT05656664 — N/A

Arsenic Poisoning Research Study Groups: Placebo, Folic Acid

Arsenic Poisoning Clinical Trial 2023: Folic Acid Highlights & Side Effects. Trial Name: NCT05656664 — N/A

Folic Acid (Vitamin) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05656664 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an age threshold for potential participants of this trial?

"This study is open to individuals aged 18 or older, up until those nearing their nonagenarian years."

Answered by AI

Are applicants currently being accepted into this research endeavor?

"According to the clinicaltrials.gov information, this research investigation is not accepting participants at this time. The study was first posted on January 1st 2023 and most recently modified in December of 2022. Subsequently, there are currently one other studies searching for patients instead."

Answered by AI

Who is authorized to participate in this research endeavor?

"This clinical trial is accepting 100 people aged 18 to 89 who have experienced arsenic or related compound-induced adverse effects. Other essential requirements for enrolment include: being an area resident, having no remarkable changes in health over the preceding 4 weeks, and written consent from each participant."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mitigation Efforts in Arsenic Exposure With Folic Acid Supplementation

Kevin Dsouza, MD 2023. "Mitigation Efforts in Arsenic Exposure With Folic Acid Supplementation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05656664.