CLINICAL TRIAL

eXciteOSA for Sleep Apnea Syndromes

EnrollingByInvitation · 18+ · All Sexes · Saint Louis, MO

eXciteOSA for Treatment of Moderate Obstructive Sleep Apnea

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About the trial for Sleep Apnea Syndromes

Eligible Conditions
Sleep Apnea Syndromes · Sleep Apnea, Obstructive · Apnea

Treatment Groups

This trial involves 2 different treatments. EXciteOSA is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Experimental Group 1
eXciteOSA
DEVICE
Experimental Group 2
eXciteOSA
DEVICE

Eligibility

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Aged >=18 years;
Diagnosed with moderate OSA;
You have a smartphone or tablet capable of running the eXciteOSA app. show original
Fluent in written and spoken English.
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Six weeks
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Six weeks.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether eXciteOSA will improve 1 primary outcome in patients with Sleep Apnea Syndromes. Measurement will happen over the course of Six weeks.

The difference in the delta-REI (baseline to follow-up) between therapy (Dose-A and Dose-B combined) and no therapy
SIX WEEKS

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can apnea be cured?

Apnea can be cured from a sleep test. It can be a simple test and can be easily controlled. It is important in the treatment of OSA.

Anonymous Patient Answer

What are common treatments for apnea?

Apnea may or may not be corrected with CPAP or bilevel positive airway pressure (BiPAP). It can also or can not be corrected with standard treatment methods where CPAP or BiPAP are not appropriate, or to the patient's preference. There are multiple potential complications associated with apneas including decompensation of other conditions such as sleep apnea and pulmonary hypertension.\n

Anonymous Patient Answer

What is apnea?

Apnea is a rare breathing pattern in pediatric patients, which may mimic a heart attack. The condition is not serious, however. It can be associated with the following underlying illnesses: neurological conditions and congenitally-related conditions.

Anonymous Patient Answer

What causes apnea?

In this population of otherwise healthy patients, the most common causes of apnea in this large group of patients were: asthma or congestive heart failure, followed by neurologic disease and COPD, followed by medication-related respiratory failure and seizure events. The remainder of the patients had a variety of other etiologies. Apnea can occur from a range of organic or non-organic causes, the most common being CNS or neuromuscular diseases.

Anonymous Patient Answer

What are the signs of apnea?

The signs of apnea are similar to those of other abnormal respiratory events. Signs include increased efforts of breathing, apneas, and a variety of breathing sounds. Because the first signs of apnea usually indicate a worse outcome than the later signs, this is a helpful tool for emergency physicians.

Anonymous Patient Answer

How many people get apnea a year in the United States?

The prevalence of obstructive sleep-disordered breathing is nearly 20 percent in the general population. Findings from a recent study, 3.9 percent of the general population will be diagnosed with sleep apnea. Rates of sleep apnea are slightly higher in men than in women. As a group, people with sleep apnea may be more likely than the general population to be obese and to have a family history of sleep apnea or hypertension.

Anonymous Patient Answer

What is the primary cause of apnea?

Apnea is an important and common clinical feature of pulmonary edema. Primary hypoxia of respiration, which can be caused by pulmonary edema, is the most common primary cause of apnea in patients with pulmonary edema. This is not to be confused with sleep apnea syndrome, which is a serious medical condition that is often diagnosed in the absence of pulmonary edema. Physicians should therefore address patients with hypoxemia (low blood oxygen) due to pulmonary edema to evaluate for sleep apnea symptom and to treat sleep apnea in those without hypoxemia despite pulmonary edema.

Anonymous Patient Answer

Has exciteosa proven to be more effective than a placebo?

In a recent study, findings suggest that the use of an exciteosin spray is safe and might be more helpful than a placebo to the treatment of OSAHS in pediatric patients.

Anonymous Patient Answer

What is the latest research for apnea?

Apnea should be considered in the differential diagnosis of children who are more than 12 months of age with excessive daytime sleepiness, and especially in the presence of hypopnea.

Anonymous Patient Answer

What are the common side effects of exciteosa?

Some common side effects may include headache, weakness (asthenia), insomnia, irritability, anxiety, palpitations, depression (due to fatigue), confusion, and hallucinations. Most people with exciteosa will get these symptoms without having a seizure. These symptoms can decrease after taking a prescription medication to treat excitement disorder. However, the use of excitement disorder medications may increase the risk of seizures. Most people with excitement disorder are monitored closely by a clinician. Most people with exciteosa may be prescribed a mood stabilizer (e.g. lithium or carbamazepine) if their excitement is severe or they do not take their medication on time.

Anonymous Patient Answer

Have there been other clinical trials involving exciteosa?

Currently there are only a few placebo controlled trials to show the effectiveness of exciteosa. These studies provide some evidence for the efficacy of exciteosa.

Anonymous Patient Answer

What are the latest developments in exciteosa for therapeutic use?

The use of Exciteosa has expanded significantly in recent years. A wider spectrum of uses is evident including in pediatric and adult patients, in a pediatric intensive care setting, and in patients with comorbities such as dementia and chronic kidney disease. As our patient population continues to mature into adulthood, this drug will inevitably be applied to pediatric patients.

Anonymous Patient Answer
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