Personalized Treatment for Obstructive Sleep Apnea
(PRAISE Trial)
Trial Summary
What is the purpose of this trial?
The purpose of this research is to see how effective the Personalized obstructive sleep apnea (OSA) Treatment Adherence Model called PRAISE is in helping the patient stick to the physician recommended OSA treatment plan Positive Airway Pressure (PAP).
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Personalized Obstructive Sleep Apnea Treatment?
Research shows that bilevel positive airway pressure (BPAP) can be an effective alternative for patients with obstructive sleep apnea (OSA) who do not respond well to continuous positive airway pressure (CPAP). BPAP may improve treatment adherence and outcomes, especially in patients who struggle with CPAP, by providing a more comfortable and adjustable pressure support.12345
Is personalized treatment for obstructive sleep apnea safe for humans?
Positive airway pressure therapies, including CPAP and bilevel PAP, have been used for decades to treat obstructive sleep apnea and are generally considered safe for humans. Some people may experience issues with comfort or side effects, but different modes of therapy can help alleviate these problems.13467
How is Personalized OSA Treatment different from other treatments for obstructive sleep apnea?
Personalized OSA Treatment is unique because it tailors the therapy to the individual's specific needs, using advanced technology to adjust the pressure levels automatically based on the patient's breathing patterns. This personalized approach aims to improve treatment effectiveness and patient comfort compared to standard treatments like fixed-pressure CPAP.1891011
Research Team
Girardin Jean-Louis, PhD
Principal Investigator
University of Miami
Eligibility Criteria
This trial is for African American, African, Caribbean or black individuals aged 60-85 with obstructive sleep apnea (OSA). Participants must be reachable by phone and give consent to release medical data. It's not for those planning to move soon, with terminal illnesses, or cognitive impairments that prevent participation.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive personalized or standard of care OSA treatment for sleep apnea
Follow-up
Participants are monitored for changes in various biomarkers and cognitive functions
Treatment Details
Interventions
- Personalized OSA Treatment
Personalized OSA Treatment is already approved in United States, European Union, Canada, Japan for the following indications:
- Obstructive Sleep Apnea
- Obstructive Sleep Apnea
- Obstructive Sleep Apnea
- Obstructive Sleep Apnea
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Miami
Lead Sponsor
National Institute on Aging (NIA)
Collaborator