Resilience Intervention for Sickle Cell Disease

Overseen By Abby Rosenberg, MD

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Boston Children's Hospital

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

25 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a resilience-promoting intervention through a Collaborative Care Model. The primary goal is to determine with the resilience intervention (PRISM) is feasible and acceptable for adolescents and young adults with SCD. Exploratory outcomes include whether this intervention improves depression, anxiety, and pain interference.

Are You a Good Fit for This Trial?

This trial is for adolescents and young adults aged 12 to 25 with Sickle Cell Disease who are experiencing depression or anxiety. They must be getting care at the DFCI/BCH Blood Disorders Center, able to participate in sessions, complete surveys in English or Spanish, and adhere to the study schedule.

Inclusion Criteria

I am receiving care at the DFCI/BCH Blood Disorders Center.

I can read and understand either English or Spanish.

I am between 12 and 25 years old.

What Are the Treatments Tested in This Trial?

Interventions

• Promoting Resilience in Stress Management

Trial Overview The study is testing a resilience-promoting intervention called PRISM within a Collaborative Care Model for those with SCD. It aims to see if this approach is workable and helpful in improving mental health and reducing pain interference.

How Is the Trial Designed?

Group I: CoCM+PRISM Experimental Treatment 2 Interventions

Collaborative Care Model (CoCM) includes a care manager, a defined population of patents/registry for tracking inclusion and progress, validated patient-reported outcome measures, and weekly inter-professional team meetings. This arm includes the use of an inter professional team to triage, plan and deliver care. the PRISM intervention, a brief, skills-based program targeting 4 resilience resources, will be delivered 1:1 as part of this treatment arm.

Who Is Running the Clinical Trial?

Boston Children's Hospital

Lead Sponsor

Trials

801

Recruited

5,584,000+

National Institutes of Health (NIH)

Collaborator

Trials

2,896

Recruited

8,053,000+