Hyaluronic Acid Filler for Cosmetic Improvement
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new approach to using hyaluronic acid (HA) fillers for cosmetic facial improvements. The focus is on achieving a balanced and complete look by layering HA fillers from the Restylane line to address hollowness or sagging in various facial areas. This method suits individuals noticing significant volume loss or sagging in the midface or lower face, such as the chin or lips. Participants should be in good health, with no recent facial surgeries or filler treatments, and no conditions affecting their skin or nerves. As an unphased trial, this study allows participants to explore innovative cosmetic solutions before they become widely available.
Will I have to stop taking my current medications?
The trial requires participants to stop taking over-the-counter NSAIDs (like Advil) at least two weeks before treatment. Participants must also not take immunosuppressants or have bleeding disorders that require thrombolytics or anticoagulants.
What prior data suggests that this pan-facial layering technique is safe?
Research has shown that Restylane injectables, a type of hyaluronic acid (HA) filler, are generally safe. The FDA has approved Restylane, and it has been used for over 20 years, demonstrating its safety.
Studies have found that some common side effects can occur, including swelling, pain, redness, and bruising at the injection site. Less common effects might include lumps, firmness, and itching. These side effects are usually mild and resolve on their own.
Overall, patients have tolerated Restylane products well. Its long history of use and approval for different facial areas supports its safety. However, individuals with severe allergies or specific sensitivities should avoid these fillers.12345Why are researchers excited about this trial?
Most treatments for facial volume loss and cosmetic improvement, like traditional fillers, focus on adding volume to specific areas. But the hyaluronic acid filler used here, Restylane Injectables, is applied using a technique called pan-facial layering. This approach targets multiple layers and areas of the face simultaneously, addressing both midface and lower face deficits. Researchers are excited about this technique because it could offer a more balanced and natural-looking rejuvenation, potentially enhancing the overall symmetry and youthfulness of the face compared to other fillers that typically focus on isolated regions.
What evidence suggests that pan-facial layering of hyaluronic acid filler is effective for cosmetic improvement?
Studies have shown that hyaluronic acid fillers, like those in the Restylane line, effectively improve facial features. In this trial, participants will receive Restylane injectables to address primary deficits in either the midface or lower face. Research indicates that Restylane Defyne is safe and significantly enhances the chin's appearance. One study found that these fillers can reduce signs of aging, such as loss of volume in the midface and a receding chin. Notably, over 94% of people and doctors observed visible improvements after using Restylane, with effects lasting up to a year. This makes Restylane a reliable choice for enhancing facial features.25678
Who Is on the Research Team?
Andreas Nikolis, MD
Principal Investigator
Erevan Innovations Inc.
Are You a Good Fit for This Trial?
This trial is for individuals seeking cosmetic enhancement with facial aesthetic concerns. It's designed for those who could benefit from a tailored approach using hyaluronic acid fillers, specifically the Restylane products. The eligibility criteria are not fully detailed here.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive pan-facial, multilayering treatment with hyaluronic acid fillers
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Pan-Facial Layering of Hyaluronic Acid Filler
Find a Clinic Near You
Who Is Running the Clinical Trial?
Erevna Innovations Inc.
Lead Sponsor