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Magnetic Resonance Spectroscopy

MRS Brain Imaging for Normal Brain Function

N/A
Recruiting
Led By Li An, Ph.D.
Research Sponsored by National Institute of Mental Health (NIMH)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18-65 years of age
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up prospective and ongoing
Awards & highlights

Study Summary

This trial will use magnetic resonance spectroscopy to study how the brain metabolizes glucose into specific chemical transmitters. This will help researchers understand how different neurotransmitters are produced.

Who is the study for?
This trial is for healthy adults aged 18-65 who can consent to participate. They must be enrolled in specific protocols, have no serious medical conditions, not use certain psychotropic drugs or substances, and cannot be pregnant or breastfeeding. People with metal implants affected by MRI or claustrophobia are also excluded.Check my eligibility
What is being tested?
The study uses advanced MRS technology at different strengths (3T and 7T) to track how the brain processes glucose into neurotransmitters like glutamate and GABA. It's a non-invasive way to understand brain metabolism in healthy individuals.See study design
What are the potential side effects?
Since this study involves MRS scans which are similar to MRIs, side effects might include discomfort from lying still during the scan or anxiety due to being in an enclosed space. There's no exposure to radiation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 65 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~prospective and ongoing
This trial's timeline: 3 weeks for screening, Varies for treatment, and prospective and ongoing for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The is the quality of the MR spectroscopy which includes spectrum signal-to-noise (SNR)\ ratio, spectral lineshape, linewidth, and resolution.
Secondary outcome measures
The is the performance improvements of the scanner hardware, software and methodology

Trial Design

1Treatment groups
Experimental Treatment
Group I: One armExperimental Treatment1 Intervention
Subjects receive the same test

Find a Location

Who is running the clinical trial?

National Institute of Mental Health (NIMH)Lead Sponsor
2,777 Previous Clinical Trials
2,674,172 Total Patients Enrolled
5 Trials studying Normal Physiology
3,727 Patients Enrolled for Normal Physiology
Li An, Ph.D.Principal InvestigatorNational Institute of Mental Health (NIMH)
1 Previous Clinical Trials
300 Total Patients Enrolled
Steve Li, Ph.D.Principal InvestigatorNational Institute of Mental Health (NIMH)
1 Previous Clinical Trials
300 Total Patients Enrolled

Media Library

MRS (Magnetic Resonance Spectroscopy) Clinical Trial Eligibility Overview. Trial Name: NCT00109174 — N/A
Normal Physiology Research Study Groups: One arm
Normal Physiology Clinical Trial 2023: MRS Highlights & Side Effects. Trial Name: NCT00109174 — N/A
MRS (Magnetic Resonance Spectroscopy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00109174 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any specific eligibility criteria for this experimental trial?

"200 individuals with no existing medical conditions, spanning 18-65 years of age, are needed for this study. Eligibility necessitates enrollment in Protocol 01-M-0254 or 17-M-0181 and a clean bill of health from both physical examination and documented medical history."

Answered by AI

Are individuals aged 25 or older included in this research protocol?

"This clinical trial is only available to individuals aged 18-65. However, there are 8 other studies for people under and over this age range respectively."

Answered by AI

What is the current enrollment capacity for this medical experiment?

"Indeed, the clinicaltrials.gov portal indicates that recruitment for this trial is ongoing; it has been posted since September 6th 2006 and last updated November 19th 2022. The study requires 200 participants to be sourced from two separate medical centres."

Answered by AI

Is there currently an opportunity to enroll in this experiment?

"Affirmative. The clinicaltrials.gov website attests that this clinical trial is actively recruiting participants, with the original post date being September 6th 2006 and most recent update on November 19th 2022. Altogether 200 patients are needed between two sites of recruitment."

Answered by AI
~49 spots leftby Jan 2030