Brain Zapping for Cognitive Enhancement
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how brain stimulation might improve attention and cognitive abilities. Researchers use a technique called transcranial electric stimulation (tES), which sends a mild electrical current through the scalp, to determine if it alters brain function during thinking tasks. The study involves healthy adults who will have their brain activity recorded while they relax and perform tasks, both with and without the stimulation. It seeks participants who are healthy, aged 18 to 45, and not on medication that affects thinking. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research on cognitive enhancement techniques.
Will I have to stop taking my current medications?
If you are taking any medications that affect the mind or have cognitive side effects, you will need to stop taking them to participate in this trial.
What prior data suggests that transcranial electric stimulation is safe for cognitive enhancement?
Research shows that transcranial electrical stimulation (tES) is safe. Studies indicate it is usually well-tolerated and does not cause pain. People who have experienced tES report few side effects, most of which are mild, such as a slight tingling on the skin.
Evidence supports its safety. Reviews of past studies confirm that tES has been used safely in many situations. As a noninvasive method, it does not involve surgery or entering the body, making it a low-risk option compared to other treatments.
Overall, data suggests that tES is a safe choice for those considering joining a study involving this type of brain stimulation.12345Why are researchers excited about this trial?
Transcranial electrical stimulation (tES) is unique because it offers a non-invasive way to potentially enhance cognitive function by delivering mild electrical currents to the brain, unlike standard methods like cognitive training or medication. Researchers are excited about this treatment because it directly targets brain activity, which could lead to quicker improvements in cognitive abilities without the need for drugs. This innovative approach also minimizes side effects compared to traditional pharmacological treatments, making it an appealing option for healthy adults looking to boost brain performance.
What evidence suggests that transcranial electrical stimulation is effective for cognitive enhancement?
Research has shown that transcranial electrical stimulation (tES), which participants in this trial may receive, can boost brain function. One study showed that tES significantly improved skills in number and math tasks, with success rates of 80% and 76%, respectively. Another study found that while all groups showed better cognitive performance, tES specifically enhanced the effectiveness of cognitive training. Additionally, a review of multiple studies found that tDCS, a type of tES, improved brain function with a small-to-moderate positive impact. Overall, these findings suggest that tES could effectively enhance cognitive abilities.26789
Are You a Good Fit for This Trial?
This trial is for healthy adults aged 18-45 who can perform cognitive tasks. It's not suitable for those with cognitive or motor function disorders, scalp issues, head injuries with lasting effects, seizure history, or those on certain medications.Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive transcranial electrical stimulation (tES) and sham stimulation while EEG data is recorded during resting-state and cognitive task conditions
Follow-up
Participants are monitored for any delayed effects of stimulation and cognitive performance
What Are the Treatments Tested in This Trial?
Interventions
- Transcranial electrical stimulation (tES)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Washington University School of Medicine
Lead Sponsor