Brain Zapping for Cognitive Enhancement

Overseen By Carol Cox

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Washington University School of Medicine

Must not be taking: Psychotropic, Cognitive side effects

Disqualifiers: Cognitive disorders, Head injury, Seizures, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

Duration: 2 sessions, each 1 hour, on separate days

72 Participants Needed

Trial Summary

What is the purpose of this trial?

The goal of this clinical trial is to learn about the effects of transcranial electric stimulation on attentional control and brain dynamics in healthy adults. The main questions are: Does stimulation affect how subjects exert attentional control? Do mathematical models predict brain activity changes in response to stimulation? Participants will have electroencephalography (EEG) brain data recorded while: They sit relaxed They receive stimulation, while relaxed They receive stimulation while completing computerized tasks to measure cognitive abilities ("cognitive tasks") They receive sham (ineffective) stimulation during cognitive tasks

Eligibility Criteria

This trial is for healthy adults aged 18-45 who can perform cognitive tasks. It's not suitable for those with cognitive or motor function disorders, scalp issues, head injuries with lasting effects, seizure history, or those on certain medications.

Exclusion Criteria

I have a skin condition on my scalp.

I have a condition that impacts my thinking or movement.

I have tattoos on my scalp.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive transcranial electrical stimulation (tES) and sham stimulation while EEG data is recorded during resting-state and cognitive task conditions

2 sessions, each 1 hour, on separate days

2 visits (in-person)

Follow-up

Participants are monitored for any delayed effects of stimulation and cognitive performance

2-4 weeks

Treatment Details

Interventions

• Transcranial electrical stimulation (tES)

Trial Overview The study tests how transcranial electric stimulation (tES) affects attention and brain activity in healthy adults. Participants undergo EEG recording while relaxed, during stimulation, and when doing computerized cognitive tasks.

Participant Groups

Group I: Device: Transcranial electrical stimulation (tES) including SHAM Experimental Treatment 1 Intervention

healthy adults

Who Is Running the Clinical Trial?

Washington University School of Medicine

Lead Sponsor

Trials

2,027

Recruited

2,353,000+