Sun Protection for Surgical Scar Healing
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines whether using sunscreen aids in the healing of scars after surgery. For individuals undergoing Mohs surgery to remove skin cancer, the trial tests if applying zinc-containing sunscreen to part of the scar improves its appearance. The study compares the sunscreen-treated part of the scar with the untreated part to assess any differences in appearance. Individuals who have had skin surgery on areas like the face or neck may be suitable participants, particularly if they are willing to return for a follow-up visit. As an unphased trial, this study provides participants the chance to contribute to understanding how sunscreen can enhance scar healing.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that zinc containing sunscreen is safe for post-surgical scar healing?
Research shows that sunscreens with zinc are generally safe for the skin. Studies have found that zinc can aid in wound healing. For instance, wounds treated with zinc ointment healed well without complications. Zinc also contributes to collagen production, a protein that maintains skin firmness, and supports the immune system, both crucial for healing.
No major reports indicate problems when using zinc sunscreen on wounds, suggesting it is gentle on the skin. However, like any product, some individuals might experience mild irritation or an allergic reaction. Monitoring the treated area and reporting any unusual reactions is always advisable.12345Why are researchers excited about this trial?
Researchers are excited about using zinc-containing sunscreen for surgical scar healing because it offers a protective mechanism that goes beyond traditional scar treatments, such as silicone gels or ointments. Zinc has anti-inflammatory properties and can aid in wound healing, potentially reducing scar formation when applied directly to the skin. By protecting the wound from harmful UV rays, this sunscreen could enhance scar healing and cosmetic outcomes in a way that existing treatments do not. This trial could reveal a simple yet effective approach to improving scar appearance with a commonly used skincare product.
What evidence suggests that zinc containing sunscreen is effective for surgical scar healing?
Research shows that sunscreen with zinc can aid wound healing and improve scar appearance. In this trial, participants will apply zinc-containing sunscreen to one half of their surgical wound, leaving the other half untreated. Studies have found that zinc oxide on the skin significantly reduces scar thickening, leading to improved scar outcomes. Zinc plays a vital role in collagen production and immune support, both crucial for healing. Additionally, zinc oxide in sunscreen shields healing scars from the sun, preventing them from worsening. Overall, using sunscreen with zinc may result in better-looking scars after surgery.23678
Are You a Good Fit for This Trial?
This trial is for adults over 18 who are having skin surgery in sun-exposed areas like the head, face, or neck. They must be able to consent and come back for a follow-up. It's not for pregnant individuals, prisoners, those under 18, anyone unwilling to return after 3 months, people allergic to zinc sunscreen, or with collagen vascular disease.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo linear repair of cutaneous surgical defects with randomized application of sunscreen to half of the wound
Evaluation
Evaluation of the scar using the patient observer scar assessment scale (POSAS) and colorimeter measurements
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Zinc containing sunscreen
Trial Overview
The study tests if zinc sunscreen affects how surgical scars heal and look after Mohs surgery. It's a split-wound trial where one part of the scar gets sunscreen and the other doesn't. After three months, they'll check scar appearance using special scales and instruments.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
The study participant will be instructed to start applying the sunscreen provided to them to the randomly assigned half of the wound (A or B).
The study participant will be instructed to not apply the sunscreen provided to them to the randomly assigned half of the wound (A or B).
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Davis
Lead Sponsor
Citations
Sun Protection for Surgical Scar Healing
Half of the wound will be treated with zinc containing sunscreen and the other half of the wound would not be treated.
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