Early vs Late TAP Block for Postoperative Pain in Prostate Cancer
(TAPBlock Trial)
Trial Summary
What is the purpose of this trial?
Determine the impact of a laparoscopic-guided transversus abdominis plane (TAP) block timing (at initiation or conclusion of procedure) on the postoperative pain experience in patients following robot assisted laparoscopic radical prostatectomy (RALP).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Early TAP Block and Late TAP Block for postoperative pain in prostate cancer?
Is the TAP block generally safe for humans?
How does the TAP block treatment for postoperative pain in prostate cancer differ from other treatments?
The TAP block (transversus abdominis plane block) is a unique treatment for postoperative pain management in prostate cancer surgeries because it involves an injection of anesthetic near the abdominal muscles to block pain signals, unlike traditional methods like epidurals or wound infiltration. This approach can reduce the need for opioids like morphine and may offer better pain control with fewer side effects.12345
Research Team
S. Mohammad Jafri, MD
Principal Investigator
Corewell Health William Beaumont University Hospital
Eligibility Criteria
This trial is for men over 18 with confirmed prostate cancer, who can read and understand the study forms, provide consent, and are scheduled for routine robotic-assisted surgery. It's not for those under 40 kg, using opioids daily for more than 3 months, with a high anesthesia risk score (ASA V), or lack of normal sensation in abdomen/pelvis.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a laparoscopic TAP block either at the initiation or conclusion of the RALP procedure
Follow-up
Participants are monitored for postoperative pain levels, opioid consumption, and other recovery metrics
Long-term follow-up
Participants are monitored for any readmission due to pain and overall recovery
Treatment Details
Interventions
- Early TAP Block
- Late TAP Block
Find a Clinic Near You
Who Is Running the Clinical Trial?
William Beaumont Hospitals
Lead Sponsor