← Back to Search

Early vs Late TAP Block for Postoperative Pain in Prostate Cancer (TAPBlock Trial)

Phase 4

Waitlist Available

Led By S. Mohammad Jafri, MD

Research Sponsored by William Beaumont Hospitals

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Men ≥ 18 years of age.

Pathologically confirmed diagnosis of prostate cancer

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 hours after ralp

Awards & highlights

TAPBlock Trial Summary

This trial evaluates whether giving a TAP block during or after robot-assisted prostate surgery affects post-op pain.

Who is the study for?

This trial is for men over 18 with confirmed prostate cancer, who can read and understand the study forms, provide consent, and are scheduled for routine robotic-assisted surgery. It's not for those under 40 kg, using opioids daily for more than 3 months, with a high anesthesia risk score (ASA V), or lack of normal sensation in abdomen/pelvis.Check my eligibility

What is being tested?

The study tests if the timing of a TAP block—a type of numbing medication given around the abdominal muscles—either at the start or end of robotic-assisted prostate surgery affects postoperative pain levels.See study design

What are the potential side effects?

While specific side effects aren't listed here, TAP blocks may generally cause discomfort at injection site, bleeding or hematoma formation; rare risks include infection and injury to internal organs.

TAPBlock Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am a man aged 18 or older.

Select...

I have been diagnosed with prostate cancer through a biopsy.

TAPBlock Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 hours after ralp

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 hours after ralp

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours after ralp for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Compare laparoscopic-guided TAP block timing (at initiation "early" or conclusion "late" of procedure) on the postoperative pain levels reported in patients following robot assisted laparoscopic radical prostatectomy (RALP).

Secondary outcome measures

Compare the effects of TAP Block timing on ambulation

Compare the effects of TAP Block timing on hospital length of stay

Compare the effects of TAP Block timing on postoperative nausea/vomiting

+4 more

TAPBlock Trial Design

2Treatment groups

Experimental Treatment

Group I: Late TAP BlockExperimental Treatment1 Intervention

For treatment delivery, subjects will receive 60 mL of 0.25 percent ropivacaine with 4 mg of dexamethasone either at the conclusion of the procedure (immediately preceding removal of the robotic / laparoscopic camera port).

Group II: Early TAP BlockExperimental Treatment1 Intervention

For treatment delivery, subjects will receive 60 mL of 0.25 percent ropivacaine with 4 mg of dexamethasone at the initiation of the procedure (immediately following placement of the robotic / laparoscopic camera port).

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

William Beaumont HospitalsLead Sponsor

149 Previous Clinical Trials

112,764 Total Patients Enrolled

7 Trials studying Prostate Cancer

2,258 Patients Enrolled for Prostate Cancer

S. Mohammad Jafri, MDPrincipal InvestigatorBeaumont Hospital Royal Oak

Media Library

Early TAP Block Clinical Trial Eligibility Overview. Trial Name: NCT05753046 — Phase 4

Prostate Cancer Research Study Groups: Early TAP Block, Late TAP Block

Prostate Cancer Clinical Trial 2023: Early TAP Block Highlights & Side Effects. Trial Name: NCT05753046 — Phase 4

Early TAP Block 2023 Treatment Timeline for Medical Study. Trial Name: NCT05753046 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the Early TAP Block received governmental authorization?

"We rate Early TAP Block's safety as a 3 due to its Phase 4 status, indicating that it has already been approved by regulatory authorities."

Answered by AI

Is this experiment actively enrolling participants?

"Clinicaltrials.gov reveals that this clinical trial, initially published on April 1st 2023 and last edited two months later, is no longer recruiting participants. Yet, there are 1764 other active trials currently seeking eligible candidates."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain

S Mohammad Jafri 2024. "Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05753046.