Morphine for Pain, Postoperative

Phase-Based Progress Estimates
University of Chicago, Chicago, IL
Pain, Postoperative
Placebo - Other
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether intrathecal morphine will decrease postoperative pain and analgesic consumption after VATS. Morphine is used to treat pain and postoperative pain.

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Other trials for Pain, Postoperative

Study Objectives

1 Primary · 7 Secondary · Reporting Duration: 1 month and 3 months after surgery

Month 3
Self reported use of analgesic medications
pain qualities
self-reported limitation of daily activity at 1 and 3 months
24 hours after surgery
Postoperative morphine equivalent consumption
Hour 48
Postoperative pain
Day 3
Self-reported patient satisfaction
Hour 48
Number of pain interventions
Postoperative opioid related side effects

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Other trials for Pain, Postoperative

Trial Design

2 Treatment Groups

1 of 2
1 of 2
Active Control
Non-Treatment Group

90 Total Participants · 2 Treatment Groups

Primary Treatment: Morphine · Has Placebo Group · Phase 4

PlaceboComparator Group · 1 Intervention: Morphine Sulfate · Intervention Types: Drug
ActiveComparator Group · 1 Intervention: Placebo · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 month and 3 months after surgery
Closest Location: University of Chicago · Chicago, IL
Photo of University of Chicago 1Photo of University of Chicago 2Photo of University of Chicago 3
2004First Recorded Clinical Trial
1 TrialsResearching Pain, Postoperative
712 CompletedClinical Trials

Who is running the clinical trial?

University of ChicagoLead Sponsor
909 Previous Clinical Trials
726,857 Total Patients Enrolled
1 Trials studying Pain, Postoperative
200 Patients Enrolled for Pain, Postoperative

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are undergoing elective video-assisted thoracoscopic surgery for anatomical lung resection.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.