Morphine for Pain, Postoperative
Phase-Based Progress Estimates
Effectiveness
Safety
University of Chicago, Chicago, IL
Pain, Postoperative
Placebo - OtherEligibility
18+
All Sexes
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Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary
This trial is testing whether intrathecal morphine will decrease postoperative pain and analgesic consumption after VATS. Morphine is used to treat pain and postoperative pain.
Treatment Effectiveness
Effectiveness Progress
This is further along than 93% of similar trials
Study Objectives
1 Primary · 7 Secondary · Reporting Duration: 1 month and 3 months after surgery
Month 3
Self reported use of analgesic medications
pain qualities
self-reported limitation of daily activity at 1 and 3 months
24 hours after surgery
Postoperative morphine equivalent consumption
Hour 48
Postoperative pain
Day 3
Self-reported patient satisfaction
Hour 48
Number of pain interventions
Postoperative opioid related side effects
Trial Safety
Safety Progress
This is further along than 85% of similar trials
Trial Design
2 Treatment Groups
Morphine
1 of 2
Placebo
1 of 2
Active Control
Non-Treatment Group
90 Total Participants · 2 Treatment Groups
Primary Treatment: Morphine · Has Placebo Group · Phase 4
Placebo
Drug
PlaceboComparator Group · 1 Intervention: Morphine Sulfate · Intervention Types: DrugMorphine
Other
ActiveComparator Group · 1 Intervention: Placebo · Intervention Types: OtherTrial Logistics
Trial Timeline
Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 month and 3 months after surgery
Closest Location: University of Chicago · Chicago, IL
2004First Recorded Clinical Trial
1 TrialsResearching Pain, Postoperative
712 CompletedClinical Trials
Who is running the clinical trial?
University of ChicagoLead Sponsor
909 Previous Clinical Trials
726,857 Total Patients Enrolled
1 Trials studying Pain, Postoperative
200 Patients Enrolled for Pain, Postoperative
Eligibility Criteria
Age 18+ · All Participants · 3 Total Inclusion Criteria
Mark “yes” if the following statements are true for you:You are undergoing elective video-assisted thoracoscopic surgery for anatomical lung resection.
About The Reviewer
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
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Cancer Related
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