Buprenorphine + Oxycodone for Acute Pain
(EASE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Traumatic injury is responsible for over 25 million (16%) Emergency Department visits and over 225,000 deaths each year per 2021 Center for Disease Control data. This is the 3rd leading cause of death in the US. Often, acute care for the injured patient requires administration of pain medication for the purposes of acute pain control from injury. The mainstay of treatment for pain control has historically involved opioid pain medication.
Who Is on the Research Team?
Matthew Painter, MD, FACS
Principal Investigator
Wake Forest University Health Sciences
Are You a Good Fit for This Trial?
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either buprenorphine or oxycodone as part of a multimodal pain control regimen
Follow-up
Participants are monitored for safety and effectiveness after treatment, including pain scores and opiate use
What Are the Treatments Tested in This Trial?
Interventions
- Buprenorphine
- Oxycodone
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Standard pain control regimen with buprenorphine
Standard pain control regimen with oxycodone
Find a Clinic Near You
Who Is Running the Clinical Trial?
Wake Forest University Health Sciences
Lead Sponsor
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