102 Participants Needed

CoolSculpting for Fat Reduction

AC
Overseen ByABBVIE CALL CENTER
Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: AbbVie
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests CoolSculpting Elite, a treatment designed to reduce fat in specific areas such as under the chin, inner thighs, and the back/bra area. The goal is to gather more information about its safety and effectiveness following its approval for use. Participants will receive the treatment on one of these areas, and researchers will closely monitor their experiences and results. This trial suits individuals with visible fat in these areas who haven't experienced significant weight changes or undergone recent procedures on these spots. As a Phase 4 trial, the study focuses on understanding how this FDA-approved and effective treatment can benefit more patients.

Do I need to stop my current medications for the CoolSculpting trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinator or your doctor.

What is the safety track record for the CoolSculpting Elite System?

Research has shown that CoolSculpting Elite is generally safe and effective for reducing fat. In past studies, participants expressed high satisfaction with the results. Specifically, treatments on areas like the torso and thighs have proven both safe and effective. CoolSculpting Elite uses cryolipolysis, a method that freezes fat cells without harming the skin.

The system includes safety features that monitor skin temperature to protect the tissue. It is also FDA-cleared for treating visible fat in areas like under the chin. While most people do not experience serious side effects, some might notice temporary redness, swelling, or numbness in the treated area. These effects usually resolve on their own. Overall, the treatment has a strong safety record, making it a reliable choice for non-invasive fat reduction.12345

Why are researchers enthusiastic about this study treatment?

Researchers are excited about the CoolSculpting Elite System for fat reduction because it offers a non-invasive alternative to traditional options like liposuction. Unlike surgical procedures that require incisions and recovery time, CoolSculpting uses controlled cooling to freeze and eliminate fat cells, allowing for a more comfortable and convenient experience. This treatment is applied to specific areas such as the submental region, inner thighs, and back/bra area, making it versatile for targeting stubborn fat pockets. Additionally, it provides a safer option with minimal downtime, which is why it's generating quite a buzz in the world of fat reduction.

What is the effectiveness track record for CoolSculpting Elite in reducing fat in specific body areas?

Research has shown that CoolSculpting Elite effectively reduces fat in specific areas. In this trial, participants will receive applications of the CoolSculpting Elite System in various body areas. Studies have found that in the area under the chin, patients can expect a 20-25% reduction in fat. Similar results occur in the inner thighs, with up to 25% of fat cells removed. In the back or bra area, the treatment also reduces fat by 20-25%. Many patients report satisfaction with the results. Overall, CoolSculpting Elite is a proven method for reducing fat without surgery.26789

Who Is on the Research Team?

AI

ABBVIE INC.

Principal Investigator

AbbVie

Are You a Good Fit for This Trial?

This trial is for individuals seeking non-invasive fat reduction in specific areas: under the chin, inner thighs, and back/bra regions. Participants should be looking for cosmetic improvements and willing to undergo CoolSculpting treatments with the Elite System.

Inclusion Criteria

Participant has clearly visible fat on the submental, bilateral inner thigh or bilateral back/bra areas, which in the investigator's opinion, is appropriate for treatment with CoolSculpting Elite.
Participant has not had weight change exceeding 5% of body weight in the preceding month.

Exclusion Criteria

I've had a body shaping procedure in the last year.
I had surgery in the treatment area within the last 6 months.
I have had surgery or a procedure to reduce fat in the area to be treated.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive applications of the CoolSculpting Elite System in the submental, inner thigh, and back/bra areas

1-2 weeks
1-2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including collection of standardized photos and satisfaction questionnaires

Up to 6 months

What Are the Treatments Tested in This Trial?

Interventions

  • CoolSculpting Elite System
Trial Overview The study tests the CoolSculpting Elite System's safety and effectiveness for reducing subcutaneous fat non-invasively in targeted body areas. It involves standardized photos and satisfaction surveys post-treatment.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Group I: Cohort C: Back/BraExperimental Treatment1 Intervention
Group II: Cohort B: Inner ThighExperimental Treatment1 Intervention
Group III: Cohort A: SubmentalExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

AbbVie

Lead Sponsor

Trials
1,079
Recruited
535,000+
Founded
2013
Headquarters
North Chicago, USA
Known For
Immunology treatments
Top Products
Humira (adalimumab), Skyrizi (risankizumab), Rinvoq (upadacitinib)

Dr. Roopal Thakkar

AbbVie

Chief Medical Officer since 2023

MD from Wayne State University School of Medicine

Robert A. Michael profile image

Robert A. Michael

AbbVie

Chief Executive Officer

Bachelor's degree in Finance from the University of Illinois

Citations

Back Fat and Bra Fat Before and After12 weeks after three CoolSculpting Elite treatments on her abdomen, flanks, back fat, and bra fat. Kenid lost 12.4 lb due to diet and exercise. CoolSculpting is ...
NCT07122583 | A Study to Assess Non-Invasive ...A Study to Assess Non-Invasive Subcutaneous Fat Reduction in the Submental, Inner Thigh and Back/​Bra Areas With the CoolSculpting Elite System · Study Overview.
CoolSculpting Elite Results That'll Make Your Jaw DropCoolSculpting before and after results typically show a 20-25% reduction in fat layer thickness in treated areas, with full results visible 3-6 months after ...
The Naked Truth: CoolSculpting EliteIn fact, CoolSculpting Elite has been clinically proven to reduce fat by up to 25%! CoolSculpting Elite freezes and permanently eliminates your fat cells. After ...
How Much Fat Can You Lose with CoolSculpting Elite?Studies and clinical trials have shown that CoolSculpting Elite can reduce fat in the treated area by up to 20-25% after a single session.
Safety, Effectiveness, and Participant Satisfaction With ...Multiple simultaneous cryolipolysis treatments on the torso using a dual-applicator system were safe and effective, with high overall participant satisfaction.
About CoolSculpting® EliteThe CoolSculpting® Elite procedure is FDA-cleared for the treatment of visible fat bulges in the submental (under the chin) and submandibular (under the jawline) ...
User Manual CoolSculpting® Elite SystemTherefore, the system monitors tissue during cooling and employs multiple safety features including the Freeze Detect® system, to minimize the risk of damage to ...
November 5, 2021 Zeltiq Aesthetics, Inc. Vicky Chai Associate ...The CoolSculpting Elite System has undergone electrical and mechanical safety performance testing and electromagnetic compatibility testing ...
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