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Calcium Channel Blocker

Amlodipine for Hypertension

Phase 4
Waitlist Available
Research Sponsored by Prisma Health-Upstate
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through hospital stay, on average 2-5 days
Awards & highlights

Study Summary

This trial is testing if amlodipine is just as effective as nifedipine ER in managing hypertension in postpartum women.

Eligible Conditions
  • Pregnancy-Induced Hypertension (PIH)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through hospital stay, on average 2-5 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and through hospital stay, on average 2-5 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Length of stay
Secondary outcome measures
Breastfeeding duration
Antihypertensive Agents
Number of patients discontinuing medication due to side effects
+3 more

Side effects data

From 2019 Phase 4 trial • 44 Patients • NCT02034435
7%
Headache
4%
numbness
4%
Dizziness/Lightheadedness
4%
viral illness
4%
Low glucose
4%
Nausea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Aim 1- Low Sodium
Aim 2- Amlodipine
Aim 2- Eplerenone
Aim 1- High Sodium

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: AmlodipineExperimental Treatment1 Intervention
Group II: Nifedipine ERActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Amlodipine
FDA approved

Find a Location

Who is running the clinical trial?

Prisma Health-UpstateLead Sponsor
82 Previous Clinical Trials
42,806 Total Patients Enrolled
1 Trials studying Hypertension
202 Patients Enrolled for Hypertension

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Could Amlodipine lead to adverse outcomes in individuals taking it?

"As this is a Phase 4 trial and thus widely approved, the safety of Amlodipine registers at 3 on our team's scale."

Answered by AI

How many participants are currently enrolled in this research endeavor?

"Affirmative. Clinicaltrial.gov's records demonstrate that this scientific experiment is actively searching for participants, with recruitment beginning on April 11th 2021 and being updated most recently on September 26th 2022. This initiative requires 132 individuals to be sourced from one medical facility."

Answered by AI

Is this a pioneering research endeavor?

"Presently, Amlodipine is being studied in 39 distinct trials across 194 cities and 24 nations. This research first began with a Phase 2 clinical trial sponsored by Encysive Pharmaceuticals back in 2007 which included 27 participants. Since then, 389 studies have been carried out on the topic."

Answered by AI

What indications does Amlodipine usually address?

"Amlodipine is conventionally prescribed to halt premature labour, but also has a role in treating pulmonary hypertension and anal fissures. Additionally, it can be employed if dietary changes fail to make an impact on certain conditions."

Answered by AI

Is enrollment currently available for this clinical trial?

"Indeed, the information on clinicaltrials.gov suggests that enrollment is now open for this medical trial. It was first publicized in April 2021 and has been recently updated on September 26th 2022. A total of 132 individuals are expected to take part from a single location."

Answered by AI

What other scientific investigations have been undertaken with Amlodipine?

"Presently, Amlodipine is being test in 392 clinical trials with 9 of those studies at the Phase 3 level. Of these locations, a notable amount are based in Boston, Massachusetts while the rest are dispersed across different parts of the globe."

Answered by AI
~33 spots leftby Apr 2025