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Pentoxifylline for Heart Failure
Study Summary
This trial is testing whether the drug pentoxifylline can reduce hemolysis (breakdown of red blood cells) in people with acute decompensated heart failure who require a mechanical circulatory support device.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am not pregnant, nursing, or planning to become pregnant.I have had a recent brain or eye bleed.I have heart failure and had an Impella device inserted for worsening symptoms.I am 18 years old or older.
- Group 1: Pentoxifylline Arm
- Group 2: Placebo Arm
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How has Pentoxifylline Oral Product been demonstrated to be secure for patients?
"The safety of Pentoxifylline Oral Product is rated highly at 3 since it has recently achieved Phase 4 status, signifying that this medication has been approved by regulatory bodies."
What ailments can Pentoxifylline Oral Product ameliorate?
"Pentoxifylline Oral Product has proven to be a successful remedy for alcoholic liver diseases, venous leg ulcers (VLUs), and intermittent claudication."
What research has been conducted regarding Pentoxifylline Oral Product's efficacy?
"Currently, 10 investigations are underway concerning Pentoxifylline Oral Product. Three of these clinical trials have reached the 3rd phase; 27 different medical centres across Memphis, Tennessee are hosting them."
Can individuals currently participate in this clinical experiment?
"According to the clinicaltrials.gov site, this trial is currently not accepting participants; although it was initially posted on September 15th 2021 and modified at last August 17th 2021, there are now 65 other medical studies enrolling patients right away."
What is the aggregate number of people taking part in this experiment?
"At present, the trial is no longer recruiting patients. It was first posted on September 15th 2021 and last updated on August 17th 2021. If you are searching for other trials that may be suitable, there are presently 55 studies related to hemolysis actively enrolling participants and 10 clinical trials utilizing Pentoxifylline Oral Product currently accepting applicants."
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