Local Anesthesia Techniques for Wrist Fractures

AG
MS
Overseen ByMegan Swiger, BS
Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: Sarasota Memorial Health Care System
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests three methods to numb pain for individuals with a broken wrist. It compares a supracondylar radial nerve block (an injection near the nerve to block pain), a hematoma block (pain relief injected into the swelling around the fracture), and a combination of both. The goal is to determine which method provides the most effective pain relief after the injury and during emergency room treatment. This trial may suit those who have recently broken their wrist and require non-surgical setting. As a Phase 4 trial, the research aims to understand how these FDA-approved and effective treatments can benefit more patients.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.

What is the safety track record for these anesthesia techniques?

Research shows that both supracondylar radial nerve blocks and hematoma blocks are generally safe for treating wrist fractures.

For the supracondylar radial nerve block, studies have found it can safely reduce pain during wrist fracture treatment. An ultrasound guides the procedure, making it efficient and less painful.

Hematoma blocks also have a good safety record. They involve injecting pain relief directly into the swollen area around the fracture. Studies have found this method to be safe, effective, and often preferred over general anesthesia.

When combined, these methods remain safe and effective. Both techniques ease pain without a significant increase in side effects.

Overall, previous patients have tolerated these treatments well, experiencing good pain relief during wrist fracture care.12345

Why are researchers enthusiastic about this trial?

Researchers are excited about these local anesthesia techniques for wrist fractures because they offer potentially more effective pain management options compared to traditional methods like oral analgesics or sedatives. The supracondylar radial nerve block involves a precise lidocaine injection near the radial nerve under ultrasound guidance, which can provide targeted pain relief with possibly fewer side effects. The hematoma block delivers analgesia directly into the hematoma at the fracture site, potentially offering faster and more localized pain control. The combination of these blocks could maximize pain relief by harnessing the benefits of both techniques, providing a comprehensive approach to managing fracture pain.

What evidence suggests that these local anesthesia techniques are effective for wrist fractures?

In this trial, participants will receive one of three different local anesthesia techniques for wrist fractures. Research has shown that supracondylar radial nerve blocks, which participants in one arm of this trial may receive, can be very effective for wrist fractures. Studies have found that this method often results in lower pain levels compared to other techniques. Another option in this trial is hematoma blocks, which involve injecting pain relief directly into the swollen area around the fracture. These are also considered safe and effective, especially as an alternative to general anesthesia. However, some research suggests they might only offer mild pain relief during the procedure. The trial will also study a combination of both techniques. Early results suggest it might improve pain control, but more evidence is needed to confirm this.12356

Who Is on the Research Team?

AG

Aaron Grossberg, DO

Principal Investigator

Sarasota Memorial Health Care System

Are You a Good Fit for This Trial?

This trial is for individuals with stable spine fractures or wrist fractures, specifically a type called Colles' fracture. Participants should be those seeking pain relief options in the emergency room setting.

Inclusion Criteria

I am willing and able to agree to participate in the study.
I am 18 years old or older.
I was admitted for a wrist fracture that needed to be realigned without surgery.

Exclusion Criteria

Prisoner
Allergy to lidocaine
I am under 18 years old.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Treatment

Participants receive one of three pain relief techniques: supracondylar radial nerve block, hematoma block, or a combination of both, to manage pain during wrist fracture reduction in the emergency room.

1 day
1 visit (in-person)

Follow-up

Participants are monitored for pain levels, opioid medication use, need for conscious sedation, and adverse events until discharge from the emergency room.

Until discharge

What Are the Treatments Tested in This Trial?

Interventions

  • Combination of blocks
  • Hematoma block
  • Supracondylar radial nerve block
Trial Overview The study compares three local anesthesia methods for wrist fracture pain: supracondylar radial nerve block, hematoma block, and their combination. It aims to determine which provides better pain relief post-injury and during ER treatment.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Group I: Supracondylar radial nerve blocksExperimental Treatment1 Intervention
Group II: Hematoma blocksExperimental Treatment1 Intervention
Group III: Combination of supracondylar radial nerve block and hematoma blockExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sarasota Memorial Health Care System

Lead Sponsor

Trials
5
Recruited
770+

Citations

Wrist Reduction Intervention: Supracondylar Technique for ...The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, ...
2.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/37663190/
Radial Nerve Supracondylar Block Versus Fracture ...The present study compares the analgesic efficacy of two techniques to perform non-surgical reduction: fracture hematoma block and radial nerve supracondylar ...
Supracondylar Radial Nerve Block Guided by Ultrasound ...This study aims to compare the analgesic effect of ultrasound-guided supracondylar block with that obtained through hematoma block in patients with distal ...
Ultrasound-guided supracondylar radial nerve block for ...This type of technique has been shown to be effective for pain management, has a relatively short learning curve, a low complication rate, and relatively low ...
Supracondylar Radial Nerve Block Guided by Ultrasound ...This study aims to compare the analgesic effect of ultrasound-guided supracondylar block with that obtained through hematoma block in patients ...
Radial Nerve Supracondylar Block Versus Fracture ...The study showed that both methods have similar analgesic efficacy, with both showing improvement. Despite a slight superiority of the hematoma fracture block ...
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