Tegaderm vs. Transpore Eye Tape for Eyelid Redness

Overseen By Dan Drzymalski, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Tufts Medical Center

Disqualifiers: Eyelid trauma, Eyelid piercings, Head surgery, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

Duration: During surgery

165 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial compares two types of medical tapes used to keep patients' eyes closed during surgery. It aims to find out which tape causes less eyelid irritation in patients undergoing anesthesia.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on comparing two types of eye tape, so it's unlikely that your medications would be affected, but you should confirm with the trial organizers.

What data supports the effectiveness of Tegaderm or Transpore Eye Tape for reducing eyelid redness?

Research shows that Tegaderm, a type of transparent dressing, has been effective in treating eye conditions like chronic exposure keratopathy by protecting the eye surface and surrounding skin. This suggests it may also help reduce eyelid redness by providing a protective barrier. ^{1 2 3 4 5}

How does the treatment using Tegaderm differ from other treatments for eyelid redness?

Tegaderm is a transparent adhesive dressing that is unique because it allows for easy monitoring of the skin underneath, which can help in early detection of any skin issues. Unlike other tapes that might cause more skin irritation or injury, Tegaderm is designed to be gentle on the skin, reducing the risk of redness and irritation when used on the eyelids during procedures like general anesthesia. ^{1 2 3 6 7}

Eligibility Criteria

This trial is for adults over 18 who are scheduled for any surgery requiring anesthesia, except surgeries involving the head, neck, face, eyes or mouth. It's not for those with pre-existing eyelid redness or trauma, eyelid piercings, or anyone undergoing surgery in a prone position.

Inclusion Criteria

I am scheduled for surgery that requires anesthesia.

I am 18 years old or older.

Exclusion Criteria

I will have surgery lying on my stomach.

I have had surgery on my head, brain, neck, teeth, mouth, eyes, or face.

Any patient that does not consent

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo anesthesia with Tegaderm applied to one eye and Transpore to the other

During surgery

1 visit (in-person)

Follow-up

Participants are monitored for eyelid erythema and other changes immediately after tape removal

Immediately after surgery

1 visit (in-person)

Treatment Details

Interventions

• Eye Protection
• Tegaderm Eye Tape
• Transpore Eye Tape

Trial Overview The study aims to compare Tegaderm Eye Tape and Transpore Eye Tape to see if there's a difference in causing eyelid redness after anesthesia. Participants will be randomly assigned one of the two tapes during their procedure.

Participant Groups

Group I: Transpore Right Experimental Treatment 1 Intervention

After general anesthesia is administered, Transpore will be placed on the right eye and Tegaderm will be placed on the left eye.

Group II: Tegaderm Left Experimental Treatment 1 Intervention

After general anesthesia is administered, Tegaderm will be placed on the left eye and Transpore will be placed on the right eye

Who Is Running the Clinical Trial?

Tufts Medical Center

Lead Sponsor

Trials

264

Recruited

264,000+

Findings from Research

In a study of 60 adult patients, silicone tape caused significantly less skin injury compared to standard acrylate tapes, with only 0% experiencing skin denudation versus 13.3% with standard tapes.

Patients reported higher satisfaction with silicone tape for both eyelid and facial skin conditions, scoring an average of 4.53 and 4.57 respectively, compared to 3.83 and 3.87 for standard tapes.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Comparison of Medical Adhesive Tapes in Patients at Risk of Facial Skin Trauma under Anesthesia. Zeng, LA., Lie, SA., Chong, SY.[2020]

References

1. United States pubmed.ncbi.nlm.nih.gov

The effect of Tegaderm™ versus EyeGard® on eyelid erythema during general anesthesia: a randomized-controlled trial. [2021]

2. United States pubmed.ncbi.nlm.nih.gov

Tegaderm transparent dressing (3M) for the treatment of chronic exposure keratopathy. [2019]

3. United States pubmed.ncbi.nlm.nih.gov

Comparison of Medical Adhesive Tapes in Patients at Risk of Facial Skin Trauma under Anesthesia. [2020]

4. United States pubmed.ncbi.nlm.nih.gov

Rebamipide protects against glaucoma eyedrop-induced ocular surface disorders in rabbits. [2018]

5. Nepal pubmed.ncbi.nlm.nih.gov

Safety and efficacy of cyclosporine (0.05% versus 0.09%) in dry eye disease. Is it the strength of cyclosporin that really matters? [2023]

6. United States pubmed.ncbi.nlm.nih.gov

Prospective, randomized, controlled comparison of SYSTANE UD eye drops versus VISINE INTENSIV 1% EDO eye drops for the treatment of moderate dry eye. [2022]

7. Spain pubmed.ncbi.nlm.nih.gov

[Comparison of a transparent dressing with gauze. Venous blood vessel maintenance]. [2006]