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N-acetyl Cysteine for Multiple Sclerosis (NACPMS Trial)
NACPMS Trial Summary
This trial will test whether N-acetyl cysteine (NAC) can help treat progressive multiple sclerosis. Half of patients will receive NAC, while the other half will get a placebo.
NACPMS Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.NACPMS Trial Design
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- I currently have active stomach or intestinal ulcers.My disability level is moderate to severe but I can still walk.My symptoms have been getting worse for at least 2 years.I've been on a stable treatment for my condition for over 3 months.My mobility or cognitive function has worsened in the last 2 years not due to relapses.I have a history of bleeding disorders.I am between 40 and 70 years old.I am currently being treated for cancer or was treated for spreading cancer in the last year.My condition is progressive MS.I have taken oral steroids in the last 3 months.I am taking supplements or medications with antioxidant properties.I have had an MS flare-up in the last 6 months.I cannot use birth control during the study.I have been taking dalfampridine for at least one month without changing the dose.I am not planning any surgery or to move in the next 15 months.
- Group 1: N-acetyl cysteine
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you give me a breakdown of the number of people participating in this clinical trial?
"The information available on clinicaltrials.gov indicates that this trial is currently looking for 98 patients across 1 site. The posting went up on 2/16/2022 and the most recent update was on 3/22/2022."
If a young person is interested in this research, are they able to enroll?
"This trial is only open to patients that are middle-aged, specifically those between 40 and 70 years old. However, there are 49 trials for people under 18 and 423 for senior citizens aged 65 or older."
How can I sign up for this research project?
"Eligible patients for this clinical trial must have a diagnosis of multiple sclerosis, be aged 40-70, and there are spaces for around 98 people in total."
Has the FDA acknowledged N-acetyl cysteine as a safe treatment?
"N-acetyl cysteine falls into the Phase 2 category, meaning that while there is some evidence suggesting it is safe, none of the trials thus far have looked at whether or not it is effective."
Are we still enrolling participants for this research project?
"That is correct, based on the information available on clinicaltrials.gov this trial appears to be actively recruiting patients. The trial was first posted on February 16th, 2022 and was last edited March 22nd, 2022. They are currently searching for 98 patients at 1 site."
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