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Beta Blocker

Propranolol for Prolonged Pregnancy (PROPEL Trial)

Phase 3
Waitlist Available
Led By Lisa Levine, MD, MSCE
Research Sponsored by Lisa Levine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from start of labor through delivery
Awards & highlights

PROPEL Trial Summary

This trial found that propranolol given to women in labor can help speed up the process and reduce the likelihood of needing a c-section.

PROPEL Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from delivery through hospital discharge, usually 2-4 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and from delivery through hospital discharge, usually 2-4 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mode of Delivery
Secondary outcome measures
Chorioamnionitis
Length of Labor
Maternal Morbidity
+2 more

PROPEL Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: PropranololActive Control1 Intervention
IV Propranolol - 2mg; one possible repeat dose ≥2 hours later
Group II: PlaceboPlacebo Group1 Intervention
Normal saline placebo- 2 mL; one possible repeat dose ≥2 hours later

Find a Location

Who is running the clinical trial?

Lisa LevineLead Sponsor
Lisa Levine, MD, MSCEPrincipal Investigator - University of Pennsylvania
Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Pennsylvania Hospital
1 Previous Clinical Trials
2,300 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Propranolol Rescue of Prolonged Labor
Lisa Levine 2020. "Propranolol Rescue of Prolonged Labor". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04299438.
~35 spots leftby Apr 2025
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