IV Lidocaine vs. ESP Block for Postoperative Pain
Trial Summary
What is the purpose of this trial?
This trial investigates a pain relief method for patients after open heart surgery. It involves an injection near the spine to numb the chest and back area by blocking pain signals. This approach aims to manage significant post-operative pain effectively.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you are dependent on narcotics (opioids) or have chronic pain, you may not be eligible to participate.
What data supports the effectiveness of the drug lidocaine for postoperative pain management after cardiac surgery?
Research shows that lidocaine, when used in combination with other pain relief methods like fentanyl, can help reduce pain after heart surgery. Additionally, intravenous lidocaine is being explored as a way to manage pain after surgery, although its effectiveness can vary depending on the type of surgery.12345
Is intravenous lidocaine safe for postoperative pain management?
How does the drug intravenous lidocaine differ from other treatments for postoperative pain?
Intravenous lidocaine is unique because it is administered directly into the bloodstream and is used as part of a multimodal pain management strategy to reduce opioid use after surgery. Unlike other local anesthetics, it is considered a 'high-risk' medicine and requires careful dosing and monitoring to avoid serious side effects.357810
Research Team
Archit Sharma, MD
Principal Investigator
University of Iowa
Eligibility Criteria
This trial is for English-speaking adults scheduled for elective cardiac surgery through sternotomy, specifically CABG or valve surgery. It's not suitable for those unable to consent, prisoners, emergency cases, with psychiatric issues affecting consent, pregnant women, those with certain medical conditions like severe organ dysfunction or coagulation disorders, a BMI outside of 20-35 range, drug dependencies or chronic pain.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either intravenous or erector spinae plane block administration of lidocaine for pain management post-cardiac surgery
Follow-up
Participants are monitored for safety and effectiveness after treatment, including pain scores and lidocaine plasma levels
Treatment Details
Interventions
- Administration of Lidocaine Post Cardiac Surgery via ESP Catheter
- Intravenous Administration of Lidocaine Post Cardiac Surgery
Find a Clinic Near You
Who Is Running the Clinical Trial?
Archit Sharma
Lead Sponsor