imFREE mCBT for Opioid Abuse

Phase-Based Estimates
1
Effectiveness
1
Safety
Tarzana Treatment Center, Tarzana, CA
Opioid Abuse+2 More
imFREE mCBT - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Opioid Abuse

Study Summary

This study is evaluating whether a mobile app can help people with opioid use disorder stay on treatment.

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Eligible Conditions

  • Opioid Abuse
  • Opioid-Related Disorders
  • Drug Abuse
  • Substance-Related Disorders
  • Opioid Use Disorder (OUD)

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Compared to trials

Study Objectives

This trial is evaluating whether imFREE mCBT will improve 1 primary outcome, 1 secondary outcome, and 3 other outcomes in patients with Opioid Abuse. Measurement will happen over the course of Baseline.

Baseline
DSM-V Checklist
Month 6
European Addiction Severity Index
Month 6
Medication Adherence self-report form. Unannounced medication count by phone
Throughout six months, monthly
Medical Management (MM) attendance
Urine drug screen

Trial Safety

Safety Estimate

1 of 3

Compared to trials

Trial Design

2 Treatment Groups

Health Education and pamphlet
UC imFREE Smartphone application intervention

This trial requires 200 total participants across 2 different treatment groups

This trial involves 2 different treatments. ImFREE MCBT is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

UC imFREE Smartphone application intervention
Behavioral
The imFREE condition is a 32-week tailored, interactive text messaging intervention targeting buprenorphine treatment retention and adherence as well as opioid use and associated health consequences. Following a face-to-face CBT session with a clinician, participants receive CBT skills training via daily text messaging, with content themes around relapse prevention, adherence behaviors, and personalized plans to overcome risk factors for treatment discontinuation.
Health Education and pamphlet
Behavioral
The mHealth condition will provide participants with a manualized health psychoeducation session of equivalent duration to the face-to-face CBT session delivered to imFREE participants. Content focuses on various dimensions of health and well-being. Subsequent to this session participants will receive an informational pamphlet regarding BUP and the importance of adherence. the mHealth component of the intervention comprises text reminders for scheduled MM appointments.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: throughout six months, monthly
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly throughout six months, monthly for reporting.

Who is running the study

Principal Investigator
S. G.
Suzette Glasner-Edwards, Principal Investigator
University of California, Los Angeles

Closest Location

Tarzana Treatment Center - Tarzana, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age > 18
DSM-5 diagnosis of OUD
no more than 2 weeks from the date of BUP induction
You are able to read and comprehend English at the 6th grade level. show original
able to provide informed consent
presently owns a mobile phone that can send and receive text messages

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes opioid abuse?

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The causes of opioid abuse can be traced to different societal factors through an individual's individual and family history of substance use and psychological factors in adolescence and adulthood. Effective treatment strategies should be tailored specifically to the individual.

Unverified Answer

What are the signs of opioid abuse?

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A number of signs, symptoms and risk factors identify people with opioids abuse. To achieve better health and social promotion of people with opioid abuse, more evidence of its clinical signs, symptoms and risk factors for such abuse is required.

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How many people get opioid abuse a year in the United States?

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In a 12-month period, between 2 and 7% of individuals admitted to the hospital had non-drug drug-related reasons for being admitted. The mean annual rate of non-drug prescription opioid abuse in a population of persons aged 13 to 69 years was 1.2% (range 0.8-1.7%). These estimates were based on surveys and do not represent actual use of illicit drugs.

Unverified Answer

What are common treatments for opioid abuse?

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These treatments are a result of a number of considerations, such as medical care and legal and law enforcement options. The treatments should be tailored to the needs of those needing treatment versus the need to protect the broader public. Treatment is recommended to help individuals regain control or dependence and to help protect the broader population. Most treatments require psychosocial support or training and other psychotherapeutic supports. However, a variety of approaches are available to address the needs of individuals and their families. It is often necessary to seek the advice of a psychiatrist, and other health care professionals to help meet the individualized needs of an individual.

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Can opioid abuse be cured?

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Though opiate addiction is a chronic illness, treatment may lead to reduced dependence and other improvements, thus decreasing relapse. Some, however, remain persistent in abuse despite treatment for at least 6 months after stopping their drug use and may thus continue to be in danger of experiencing further negative consequences as a result of opiate abuse. Effective treatment for opiate abuse requires comprehensive treatment plans incorporating medical, behavioral, and other treatment modalities as applicable and necessary to help such patient maintain remission.

Unverified Answer

What is opioid abuse?

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Opioid abuse is common among adults, with 10% to 30% of them dealing with addiction daily, yet awareness and education needs are usually insufficient. Efforts to decrease the health risks of drug abuse and addiction (i.e., opioid abuse) should be made.

Unverified Answer

What are the common side effects of imfree mcbt?

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The most common side effects of imfree mcbt are the side effects listed on the box. Other side effects include dizziness, headache, somnolence, rash, itchiness, and constipation. Other symptoms with smaller rates of reporting include tachycardia, sweating, diarrhea, and vomiting. There is some weak evidence that it might interfere with the effects of certain birth control methods and with antihypertensives (such as those used in treatment of high blood pressure). There is some evidence for higher rates of bleeding (due to a higher risk of bruising) in those taking aspirin and other anti-platelet medications (such as those used to treat or prevent heart attacks or stroke) while on imfree mcbt.

Unverified Answer

How serious can opioid abuse be?

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The prevalence of opioid treatment use in North Dakota is among the highest in the U.S. It is most strikingly higher in Native Americans. In spite of this high occurrence of opioid abuse, there is no clear relationship between the occurrence of opioid abuse in Native Americans and their socioeconomic status.

Unverified Answer

Has imfree mcbt proven to be more effective than a placebo?

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Results from a recent clinical trial of this meta-analysis suggest that iMitfb hasn’t demonstrated a significantly greater effect on medication-overuse headache (MOH), [neck pain] or [facial pain] when compared with a placebo. Further research is needed to confirm this conclusion.

Unverified Answer

What is imfree mcbt?

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Our patient's clinical history of drug abuse, prior use of cocaine, a history of poor performance status, and elevated white blood cells should be taken into account when deciding treatment. There is a limited and weak evidence to support the use of opioid replacement therapies as an adjunct during methadone maintenance therapy, but there is no strong evidence that they are effective in promoting abstinence.

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What is the average age someone gets opioid abuse?

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The average age of opioid abuse occurs in persons in their twenties. Data from a recent study will help clinicians with this population better understand why this group remains at risk.

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What does imfree mcbt usually treat?

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Imfree mcbt can treat common ailments like chronic pain, anxiety, and sleeping problems. It is important for the prescriber to be aware of the potential side effects when prescribing Imfree mcbt to the opioid-addicted patient. As with all drugs, it deserves to be prescribed by a professional who is familiar with its effects and who thoroughly examines all patients before prescribing it to them.

Unverified Answer
See if you qualify for this trial
Get access to this novel treatment for Opioid Abuse by sharing your contact details with the study coordinator.