This trial is studying two chemotherapy regimens to treat patients with Wilms tumor.
- Anaplastic Wilms Tumor
- Stage II Kidney Wilms Tumor
- Stage III Kidney Wilms Tumor
- Stage IV Kidney Wilms Tumor
- Wilms Tumor
1 Primary · 1 Secondary · Reporting Duration: From study entry to death due to any cause, assessed up to 5 years after study enrollment
Side Effects for
2 Treatment Groups
Arm II (Regimen ICE/Cyclo/Topo)
1 of 2
Arm I (Regimen UH-3)
1 of 2
221 Total Participants · 2 Treatment Groups
Primary Treatment: Ifosfamide · No Placebo Group · Phase 2
Who is running the clinical trial?
Age < 65 · All Participants · 10 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Are there any locations within the city that are currently conducing this research?
"Currently, participants are being recruited from 100 different sites located in cities such as Springfield, Jacksonville and West Palm Beach. To negate transitory stresses, it is suggested that those interested seek out the closest location available to them for enrollment." - Anonymous Online Contributor
Under what circumstances is Ifosfamide typically prescribed?
"Ifosfamide is frequently utilized to treat Hodgkin's Disease, as well as lymphocytic lymphomas, malevolent esophageal neoplasms, and Neuroendocrine Tumours (NETs)." - Anonymous Online Contributor
Has the Federal Drug Administration sanctioned any therapeutic uses of Ifosfamide?
"Due to the lack of existing clinical data regarding ifosfamide's efficacy, and its relative safety in Phase 2 trials, our team at Power has awarded it a score of 2." - Anonymous Online Contributor
Is this research pioneering in its field?
"As of now, 1950 active trials are underway involving Ifosfamide across the world's 88 countries in 3814 cities. The pioneering investigation for this drug was undertaken by Alfacell back in 1997 with 300 participants and concluded at Phase 3 status. Subsequently, 3217 studies have taken place since then." - Anonymous Online Contributor
Are there any precedents for the application of Ifosfamide in clinical trials?
"Ifosfamide was initially investigated at Spectrum Health Hospital - Butterworth Campus in 1997. Since then, a total of 3,217 trials have been completed and 1,950 are ongoing; many of these clinical assessments take place in Springfield, Illinois." - Anonymous Online Contributor
Is there presently any recruitment for this clinical experiment?
"Data available on clinicaltrials.gov corroborates that this study is still recruiting participants, having been posted to the website on September 18th 2020 and revised as of October 21st 2022." - Anonymous Online Contributor
What is the sample size of this experiment?
"This clinical trial mandates the participation of 221 eligible participants. Southern Illinois University School of Medicine in Springfield and Nemours Children's Clinic-Jacksonville are amongst the available sites for patients to join this experiment." - Anonymous Online Contributor