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Behavioural Intervention

Geriatric Assessment for Blood Disorders

Phase 2

Waitlist Available

Led By Richard J Lin, MD, PhD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

have a pathologically confirmed myeloid malignancies including acute myeloid leukemia, ,myelodysplastic syndrome, myeloproliferative neoplasms, or related blood disorders including chronic myelomonocytic leukemia, atypical chronic myeloid leukemia, and myelodysplastic/myeloproliferative overlapping syndrome

are 60 years or older

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial will look at whether a geriatric assessment can help improve treatment outcomes for older patients with a myeloid malignancy.

Who is the study for?

This trial is for people aged 60 or older with certain blood disorders like acute myeloid leukemia and related conditions, who have a suitable donor for stem cell transplant. They must meet the standard criteria for transplantation and have less than 10% of immature cells (blasts) in their bone marrow.Check my eligibility

What is being tested?

The study tests if a geriatric assessment before an allogeneic hematopoietic stem cell transplant can improve treatment outcomes and quality of life in older patients. This includes evaluating cognitive function, physical ability, mood, nutrition, and medications.See study design

What are the potential side effects?

Potential side effects are not specified here but may include typical risks associated with chemotherapy, stem cell transplants such as infections due to low immunity, graft-versus-host disease (GVHD), organ damage, or reactions to new stem cells.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have a confirmed diagnosis of a myeloid blood disorder.

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I am 60 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

cumulative incidence of non-relapse mortality (NRM)

Trial Design

1Treatment groups

Experimental Treatment

Group I: Geriatric participants with various blood disordersExperimental Treatment3 Interventions

Geriatric assessment (GA) pre-transplant Risk-adapted allocation of conditioning intensity based on GA GA-directed, longitudinal supportive care management

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,935 Previous Clinical Trials

588,822 Total Patients Enrolled

Richard J Lin, MD, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

Media Library

Geriatric assessment (GA) pre-transplant (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04761770 — Phase 2

Myelodysplastic Syndrome Research Study Groups: Geriatric participants with various blood disorders

Myelodysplastic Syndrome Clinical Trial 2023: Geriatric assessment (GA) pre-transplant Highlights & Side Effects. Trial Name: NCT04761770 — Phase 2

Geriatric assessment (GA) pre-transplant (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04761770 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many medical centers are currently administering this clinical trial?

"This trial has 7 total sites for recruitment, including Memorial Sloan Kettering Westchester (Consent Only) in Harrison, Memorial Sloan Kettering Nassau (Consent Only) in Uniondale and the flagship site of this project - Memorial Sloan Kettering Cancer Center (All Protocol Activities)."

Answered by AI

How many volunteers are currently being accepted into this experiment?

"Affirmative, the data hosted on clinicaltrials.gov indicates that this trial is still recruiting subjects. Initially posted on February 15th 2021, the medical study was last updated in August 24th 2022 and is seeking 32 participants spread across 7 different sites."

Answered by AI

Is the current treatment regimen approved by the Federal Drug Administration?

"Our team rated the conditioning regimen at a 2 on our scale, as there is clinical evidence which suggests it possesses some degree of safety but none to suggest efficacy."

Answered by AI

Does this medical trial have an ongoing need for participants?

"Affirmative. Clinicaltrials.gov reveals that this medical experiment, launched on February 15th 2021, is actively enlisting patients at this time. 32 people must be recruited across 7 different research sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

2021. "Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04761770.