421 Participants Needed

Reproxalap for Dry Eye Syndrome

MA
LN
CP
TB
SM
AB
CM
AW
Overseen ByAnnalisa Webb
Pivotal Trial (Near Approval)This treatment is in the last trial phase before FDA approval
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

A Multicenter, Phase 3, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Environment Exposure Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap

Are You a Good Fit for This Trial?

This trial is for individuals with Dry Eye Disease, a condition where eyes do not stay properly lubricated. Participants should have a confirmed diagnosis and may need to meet other specific health criteria set by the study.

Inclusion Criteria

I have signed the consent and HIPAA forms.
I have used or wanted to use eye drops for dry eyes in the last 6 months.

Exclusion Criteria

Use of contact lenses within 7 days of Visit 1 or anticipate using contact lenses during the trial
Use of eye drops within 2 hours of Visit 1
I do not have an eye infection or inflammation right now.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2 weeks

Treatment

Participants receive 0.25% Reproxalap Ophthalmic Solution or vehicle for dry eye disease

6 weeks
Weekly visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Reproxalap
Trial Overview The trial is testing the effectiveness of Reproxalap ophthalmic solution (0.25%) compared to a vehicle (placebo) solution in improving symptoms of dry eye. It's conducted at multiple centers, with participants randomly assigned to either treatment.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Reproxalap Ophthalmic Solution (0.25%)Experimental Treatment1 Intervention
Group II: Vehicle Ophthalmic SolutionPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Aldeyra Therapeutics, Inc.

Lead Sponsor

Trials
34
Recruited
4,700+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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