Treatment for Hernia, Inguinal

Phase-Based Estimates
1
Effectiveness
2
Safety
Memorial Hermann Hospital, Houston, TX
Hernia, Inguinal+2 More
Eligibility
18+
All Sexes
Eligible conditions
Hernia, Inguinal

Study Summary

Treatment of Occult Inguinal Hernias

See full description

Eligible Conditions

  • Hernia, Inguinal
  • Hernia
  • Inguinal Hernias

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 12 secondary outcomes in patients with Hernia, Inguinal. Measurement will happen over the course of 30 days post-operative.

Year 1
Groin pain on occult hernia side
1 year post-operative
Assessment of chronic pain
Progression of hernia signs or symptoms
1 years post-operative
Operative re-intervention
2 years post-operative
Hernia recurrence
30 days post-operative
Number of patients who develop any surgical complication
Year 2
Satisfaction with Decision Scale
Time off work due to the hernia surgery
Time to resume normal activity from any hernia surgery
Year 2
Change in Abdominal wall quality of life (AW-QOL)
Patient threshold value for need for future surgery in order to accept Expectant Management (EM) of an Occult Inguinal Hernia (OIH) determined using standard gamble technique
Time of surgery
Number of patients with an occult inguinal hernia
Time duration for surgery

Trial Safety

Safety Estimate

2 of 3
This is better than 68% of similar trials

Trial Design

1 Treatment Groups

Control

This trial requires 280 total participants across 1 different treatment groups

This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.

ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 2 years post-operative
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 2 years post-operative for reporting.

Who is running the study

Principal Investigator
J. H.
Prof. Julie Holihan, Assistant Professor of Surgery-Clinical
The University of Texas Health Science Center, Houston

Closest Location

Memorial Hermann Hospital - Houston, TX

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age 18 or older
Patients undergoing unilateral laparoscopic inguinal hernia repair, found to have a contralateral occult inguinal hernia

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get hernia, inguinal a year in the United States?

Add answer

Around 2 million Americans develop hernia each year. The peak age for herniated inguinal wall is 30 to 39 years. Men are more prone to hernia than women. This hernia affects the abdominal cavity and can extend to the scrotum. This hernia has an overall mortality rate of 0.1%. Hernia is a common problem among patients presenting with abdominal pain. Laparoscopic mesh repair is the treatment of choice.

Unverified Answer

What is hernia, inguinal?

Add answer

Most inguinal hernias occur in children. There are 2 types of hernias and they differ in symptoms and treatment strategies. The common hernia has 4 layers and is called paramesomphalicus and parieto-imperitoneal. The mesh surgery for paramesomphalic hernia can be performed using the minimally invasive laparoscopy. Treatment options for parieto-imperitoneal hernia are mesh surgery, hernia prophylaxis with propranolol (beta blocker), and inguinal hernia prophylaxis using a periurethral mesh patch (ProSeal). (c) 2007 Wiley-Liss, Inc.

Unverified Answer

What are common treatments for hernia, inguinal?

Add answer

Hernia, inguinal, is not a common disorder. The mainstay of management for the patients is surgical repair with mesh. If the mesh is not available then surgical mesh-placement can be done even if the mesh is in moderate to severe degenerative states, by applying a bio-absorbable mesh.

Unverified Answer

What are the signs of hernia, inguinal?

Add answer

Possible symptoms of hernia include vomiting (early in the course of the illness), pain in the left lower quadrant of the abdomen, inability to defecate, and swelling of the abdomen. Other symptoms are similar to those of an abdominal pain of other aetiology (gall bladder, gastritis, diverticulitis, appendicitis), as well as inguinal hernias due to an abdominal pathology. Imaging of the abdomen is of great importance. Radiographs, CT and, if possible, MRI, are the most indicated scans.

Unverified Answer

What causes hernia, inguinal?

Add answer

In the present series some cases could not be explained fully; the causes of hernia are probably multicomponent. The main predisposing factor is male sex, which explains 50% of cases of inguinal hernia. The only identifiable predisposing factor in the control population was a family member with inguinal hernia. In addition, obesity may be a predisposing factor for inguinal hernia; however, this need to have a more thorough investigation, to define the underlying factors contributing to this condition. As obese males are not found to have a higher incidence of developing hernia, obesity alone cannot be the cause of hernia.

Unverified Answer

Can hernia, inguinal be cured?

Add answer

There is potential for improvement in the current hernia paradigm. Current inguinal hernia surgery does not have a cure rate in excess of 55%-60%, although these figures have not been properly reported. There is potential for inguinal hernia therapy to be cure oriented.

Unverified Answer

What is the primary cause of hernia, inguinal?

Add answer

We recommend spermiogenesis be suspected when inguinal hernias occur in elderly patients with no medical history. We also recommend repairing the hernias if they occur with an unexplained inguinal pain or discomfort. The surgical management of hernias is highly specialized and we recommend careful follow-up.

Unverified Answer

What are the latest developments in treatment for therapeutic use?

Add answer

The study shows that in more recent literature the procedure for surgical treatment of inguinal hernia is a complex algorithm, with a range of different surgical and non-surgical technical approaches. Different surgical approaches are related to the anatomical variants and pathological aspects of the disease. Inguinal hernia repair represents the only surgical approach which can guarantee a cure in all anatomical variants, even in complex cases.

Unverified Answer

Who should consider clinical trials for hernia, inguinal?

Add answer

Hernia involves the contents of the abdomen and can be very painful. Inguinal hernias account for approximately 2% of inguinal hernias. Current medical literature does not exist to substantiate any clear guidelines for the referral of patients with inguinal and/or abdominal Hernia, to clinical trials. Therefore, it is recommended that consideration of both surgical and medical aspects be considered when deciding on which clinical trials to pursue, and that all patients with inguinal hernias or abdominal hernias be referred for testing, regardless of location.

Unverified Answer

Is treatment safe for people?

Add answer

This review highlights the important role of clinical and clinical trial outcomes in safety appraisal and, therefore, the need to assess the safety of treatments more systematically and systematically.

Unverified Answer

What is the latest research for hernia, inguinal?

Add answer

Researchers are studying the effectiveness of different types of mesh material, and the potential causes of hernias. One study looked at the possibility of mesh material breaking up in the patient's body. Doctors will evaluate a number of hernias and discuss them with patients. A great deal of effort has gone into finding a mesh material that will work and will not create a complication. Other studies have focused on the effectiveness of different types of mesh material, and scientists have found a way to make hernia repairs safer as well as more effective. Patients need to make a decision based on the study results as well as their own experience. One of the best sites for information for hernia, inguinal repairs is the American Urological Association.

Unverified Answer

Have there been any new discoveries for treating hernia, inguinal?

Add answer

There are many new discoveries for treating hernia, inguinal, including the use of [a mesh(s) that are seeded or grown in the patient's own body, but are only inserted in the body's abdominal cavity to heal and to support the skin, muscle, and fascia rather than being removed and then re-implanted.] There has been a recent report from a New York Center about treating inguinal hernia--[using the [femoral patch-technique] invented in New Jersey by Dr. [Sebastian] Farfan and [Dr.] Eugene G.

Unverified Answer
See if you qualify for this trial
Get access to this novel treatment for Hernia, Inguinal by sharing your contact details with the study coordinator.