100% Aloe Vera Juice for Laryngeal Cancer

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Thompson Cancer Survival Center Radiation Oncology Services, Knoxville, TN
Laryngeal Cancer+14 More
100% Aloe Vera Juice - DietarySupplement
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.

Eligible Conditions

  • Laryngeal Cancer
  • Radiation Mucositis
  • Oropharynx Cancers
  • Neoplasms
  • Malignant Neoplasms
  • Esophageal Neoplasms Malignant
  • Oral Cavity Cancer
  • Mediastinal Cancer

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 10 weeks

10 weeks
Management of Oral Mucositis and Esophagitis
Prevention of Oral Mucositis and Esophagitis

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

4 Treatment Groups

Cohort 1--Arm 2
1 of 4
Cohort 2-- Arm 2
1 of 4
Cohort 1--Arm 1
1 of 4
Cohort 2--Arm 1
1 of 4
Active Control
Experimental Treatment

100 Total Participants · 4 Treatment Groups

Primary Treatment: 100% Aloe Vera Juice · No Placebo Group · Phase 3

Cohort 1--Arm 1Experimental Group · 4 Interventions: Magic Mouthwash, 100% Aloe Vera Juice, Salt and Baking soda rinse, Carafate · Intervention Types: CombinationProduct, DietarySupplement, CombinationProduct, Drug
Cohort 2--Arm 1Experimental Group · 4 Interventions: Magic Mouthwash, 100% Aloe Vera Juice, Salt and Baking soda rinse, Carafate · Intervention Types: CombinationProduct, DietarySupplement, CombinationProduct, Drug
Cohort 1--Arm 2ActiveComparator Group · 3 Interventions: Magic Mouthwash, Salt and Baking soda rinse, Carafate · Intervention Types: CombinationProduct, CombinationProduct, Drug
Cohort 2-- Arm 2ActiveComparator Group · 3 Interventions: Magic Mouthwash, Salt and Baking soda rinse, Carafate · Intervention Types: CombinationProduct, CombinationProduct, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Magic Mouthwash
2015
Completed Phase 3
~80

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 10 weeks
Closest Location: Thompson Cancer Survival Center Radiation Oncology Services · Knoxville, TN
Photo of knoxville 1Photo of knoxville 2Photo of knoxville 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Laryngeal Cancer
0 CompletedClinical Trials

Who is running the clinical trial?

Thompson Cancer Survival CenterLead Sponsor
Daniel Scaperoth, MDPrincipal InvestigatorThompson Cancer Survival Center

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have signed and dated an IRB approved consent form that conforms to federal and institutional guidelines.
You are of child-bearing potential and you must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.