Treatment for Malignancies

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Texas MD Anderson Cancer Center, Houston, TX
Malignancies
Eligibility
18+
Female
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Study Summary

This study is evaluating whether a motivational interviewing intervention can help African American women stay more active.

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Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome in patients with Malignancies. Measurement will happen over the course of 7 days.

7 days
Self-reported Minutes of Moderate-intensity Physical Activity per Week

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

Intervention Group 1
1 of 3
Intervention Group 2
1 of 3
Focus Group
1 of 3
Active Control

This trial requires 80 total participants across 3 different treatment groups

This trial involves 3 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Intervention Group 1CAPMI Intervention: Training + Weekly Partner Questionnaire + Interview + PA Newsletter
Intervention Group 2Interview + PA Newsletter
Focus GroupQualitative interviews examining social support for PA conducted with African American (AA) women recruited from Wheeler Avenue Baptist Church located in Houston used to design Culturally-Appropriate Peer-based Motivational Interviewing (CAPMI) intervention.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 7 days
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 7 days for reporting.

Closest Location

University of Texas MD Anderson Cancer Center - Houston, TX

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Both partners are required to meet the same eligibility requirements and both partners will be enrolled as participants. Each woman will complete the same consent form.
African American (AA) woman (self-defined by participant) ages 18-65 years
Currently sedentary, defined as self-reported PA <3 days/week for <20 minutes/day over the past 6 months
Be ready and physically able to start being physically active, i.e., in preparation stage of change.
Able to read English at a sixth-grade level as assessed by the Rapid Estimate of Adult Literacy in Medicine (REALM)
Identify a sedentary AA female (i.e., non-intimate family member or friend) with whom they can enroll in the study
Be available to participate in weekend trainings
Have a home address where information can be mailed and working telephone.

Patient Q&A Section

What are the signs of malignancies?

"A high concern is justified on the grounds that symptoms manifesting as physical symptoms may not be readily recognised by physicians. A thorough medical history, the examination technique of the individual doctor, and a comprehensive clinical examination are the key elements for achieving a correct diagnosis to facilitate relevant treatment decisions and, consequently, reduce the mortality of malignancies." - Anonymous Online Contributor

Unverified Answer

How many people get malignancies a year in the United States?

"Most cancers and all cancer mortality rates are increasing. The most common cancers include breast, colon and rectum, prostate, colorectal, lung, larynx (meninges) and throat. There is an increase in mortality from all cancers. The highest mortality rates were for cancers, which showed a 4.9 fold average increase in annual mortality rates (2001-2007)." - Anonymous Online Contributor

Unverified Answer

What are common treatments for malignancies?

"There are various treatment options for malignant tumors of the larynx, head and neck, breast, and lung systems. Some treatment options can be surgery, radiation therapy, and/or chemotherapy; some are surgery, radiation therapy, and/or chemotherapy. There are no curative cures and treatments are directed for symptom relief and quality of life." - Anonymous Online Contributor

Unverified Answer

Can malignancies be cured?

"Today's cure rate is estimated to be 15 to 25% for some malignancies. Even if cured, people have a mortality rate that is about four times greater than that of the general population. Cure with the currently available treatment modalities is a beautiful illusion and only the dream of those who have an aggressive desire to live." - Anonymous Online Contributor

Unverified Answer

What causes malignancies?

"The most likely cause of malignancies is the natural process of aging; that is, most malignancies appear to be developmental mistakes or mistakes in cellular replication, not due to a pre-existing tumor. It is important to keep in mind that cancer is not a single entity. A single cancer may have many different origins, and the multiple origin model should be considered. There are three basic types of cancers: sarcomas, histiocytic tumors (leukemias), and epithelioid tumors (primarily lung and breast; with neuroectodermal tumors often being seen in adolescents and young adults)." - Anonymous Online Contributor

Unverified Answer

What is malignancies?

"Malignancies consist of over 20 types of cancer; however the most common type is lung cancer. Most cases of cancer are curable with the current knowledge on the disease as well as some new therapies. The average survival of a cancer-affected patient is ~10-15 years. Nevertheless, the survival rate varied between different types of cancer. Patients with non-small cell lung cancer can be treated effectively, but patients with multiple myeloma and leukemia are not. The only option for patients with pancreatic cancer is surgery to have a chance to survive for 3 months. Most other types of cancer, such as colon cancer can be cured with some type of surgery. However, the disease is not curable." - Anonymous Online Contributor

Unverified Answer

How does treatment work?

"There is little agreement between the different models of treatment response in the literature. Only a very few studies allow us to estimate response to treatment. Most studies are cross-sectional and retrospective. Most of the studies involve a limited number of tumors and only a few studies on response to treatment include control groups. However, there are some common features between the model. The most promising seems to be a combination of treatment, particularly the response to chemotherapy." - Anonymous Online Contributor

Unverified Answer

What is the latest research for malignancies?

"The majority of the research articles presented in the malignancies section could not be fully assessed, yet it was determined that there is an improvement of research and its reporting for malignancies. It is expected that more research will be generated. The quality of reporting of the reviewed articles appeared poor. [Power(https://www.withpower.com/clinical-trials/malignancies/) makes it easy to find malignancy clinical trials tailored specifically to your condition, treatment, or location." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for malignancies?

"Given this data, it may be reasonable to perform a clinical trial based on tumor type, histology, location, and age using the criteria in this article. Clinical judgment may be necessary for some tumors to warrant a clinical trial using the above criteria." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets malignancies?

"Most people get malignancies in the older decades of life. People over 40 years old had the highest rate of cancer diagnoses and deaths. However, the rate of diagnoses did not peak at this high age. In fact, the cancer death rate was higher for everyone under the age of 40 years in comparison to everyone over age 50 years. [Power(http://http://www.withpower.com/d/tables/esophagus.htm)]" - Anonymous Online Contributor

Unverified Answer

Is treatment typically used in combination with any other treatments?

"Combination treatment is the most commonly used treatment for AML, a combination with any other treatment is nearly always used for ALL, and any combination is nearly always used for MDS and CLL except for some specific combinations, such as a stem cell transplant from the matched donor, or chemotherapy with a Bortezomib combination. When it comes to the use of other treatments, there is no pattern to the combination of treatments that are typically used according to type or prognostic group of the patient." - Anonymous Online Contributor

Unverified Answer

Has treatment proven to be more effective than a placebo?

"Patients randomized to treatment and patients randomized to the placebo arm received identical treatment. Although treatment as a whole is not more effective than a placebo in rheumatoid arthritis, some anti-TNF agents show greater effects than placebo in this disorder, suggesting that a biological effect of the drug is responsible for the differences observed." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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