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Radiopharmaceutical

NaF PET Imaging for Bone Cancer

Phase 3

Recruiting

Led By Éric E Turcotte, MD

Research Sponsored by Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Able to tolerate supine position

Pediatric patients for whom a 99mTc-biphosphonate bone scintigraphy is indicated for oncologic or infectious reasons

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 17 years

Awards & highlights

Study Summary

This trial will help establish 18F-NaF as a safe and effective alternative to bone scintigraphy.

Who is the study for?

This trial is for patients who need a bone scan (99mTc-biphosphonate bone scintigraphy) due to conditions like infections, arthritis, or bone tumors. It includes adults and children with cancer or infectious diseases needing this test. Pregnant individuals, those allergic to 18F-NaF, or unable to lie flat for at least 15 minutes cannot participate.Check my eligibility

What is being tested?

The study tests the safety and effectiveness of using an imaging agent called 18F-sodium fluoride (18F-NaF) in PET scans as an alternative to standard bone scintigraphy. This could be important if there's another shortage of the usual radioactive material used in these scans.See study design

What are the potential side effects?

While specific side effects are not listed here, participants will be monitored for any adverse reactions related to the injection of the tracer substance, which may include allergic reactions or discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can lie on my back comfortably.

Select...

I am a child needing a bone scan for cancer or infection.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 17 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~17 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 17 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Correlate 18F-NaF PET images with pathology reports

Efficacy profile of 18F-NaF compared to 99mTc-biphosphonate bone scintigraphy

Safety profile of 18F-NaF

Trial Design

1Treatment groups

Experimental Treatment

Group I: 18F-NaF eligible patientsExperimental Treatment1 Intervention

Eligibility for 18F-NaF PET scans is the same than for bone scintigraphy routinely prescribed in the clinic.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Centre de recherche du Centre hospitalier universitaire de SherbrookeLead Sponsor

58 Previous Clinical Trials

28,665 Total Patients Enrolled

Université de SherbrookeOTHER

292 Previous Clinical Trials

66,941 Total Patients Enrolled

Éric E Turcotte, MDPrincipal InvestigatorUniversité de Sherbrooke, Centre de Recherche du CHUS

3 Previous Clinical Trials

6,000 Total Patients Enrolled

Media Library

18F-sodium fluoride (Radiopharmaceutical) Clinical Trial Eligibility Overview. Trial Name: NCT04842071 — Phase 3

Bone Cancer Research Study Groups: 18F-NaF eligible patients

Bone Cancer Clinical Trial 2023: 18F-sodium fluoride Highlights & Side Effects. Trial Name: NCT04842071 — Phase 3

18F-sodium fluoride (Radiopharmaceutical) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04842071 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What side effects have been linked with 18F-sodium fluoride?

"Previous clinical trials have provided some evidence of 18F-sodium fluoride's efficacy, and there is supporting data for its safety from multiple sources. Consequently, we've given it a score of 3."

Answered by AI

Are there any still open enrollment slots for this research project?

"Yes, the information available on clinicaltrials.gov indicates that this study is actively recruiting patients. The listing for this trial was first posted on January 1st 2008 and edited most recently on July 18th, 2022. This particular research project is searching for 2500 participants at 2 different locations."

Answered by AI

How many patients are currently enrolled in this experiment?

"That is accurate. The clinicaltrials.gov website currently has this information posted about the study: it was first listed on 1/1/2008, and most recently updated on 7/18/2022. There are 2500 patients needed for the trial taking place at 2 locations."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment

Dr Éric E Turcotte, MD 2008. "18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04842071.

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