Study Summary
This trial will help determine if it's better to continue or discontinue statin drugs after suffering from a spontaneous lobar intracerebral hemorrhage, and whether an individual's Apolipoprotein-E genotype should influence this decision.
- Stroke
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: Within 24 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
No-statin
1 of 2
Statin
1 of 2
Active Control
1456 Total Participants · 2 Treatment Groups
Primary Treatment: Statin · No Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
Massachusetts | 100.0% |
What site did they apply to?
Beth Israel Deaconess Medical Center | 100.0% |
What portion of applicants met pre-screening criteria?
Did not meet criteria | 100.0% |
How many prior treatments have patients received?
0 | 100.0% |
Why did patients apply to this trial?
- "I have had many stokes."
- Szejko, Natalia, Elayna Kirsch, and Guido J. Falcone. 2021. “Genetic Determinants of LDL Cholesterol and Risk of Intracerebral Haemorrhage”. Current Opinion in Lipidology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/mol.0000000000000761.
- Szejko, Natalia, Elayna Kirsch, and Guido J. Falcone. 2021. “Genetic Determinants of LDL Cholesterol and Risk of Intracerebral Haemorrhage”. Current Opinion in Lipidology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/mol.0000000000000761.
- Magdy Selim 2020. "Statins In Intracerbral Hemorrhage". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03936361.
Frequently Asked Questions
What sort of risk does Statin present to patients?
"Our team at Power estimates that Statin is safe enough to be classified as a 3 on a scale from 1 to 3. This is because Statin is currently in Phase 3 of clinical trials, meaning that there is some data supporting its efficacy, as well as multiple rounds of data supporting its safety." - Anonymous Online Contributor
Does this study have any available positions for participants?
"That is correct. As indicated on clinicaltrials.gov, this particular trial is still looking for patients. The posting date was June 10th, 2020 and the most recent update was February 28th, 2022. They are hoping to find 1,456 willing participants at a single location." - Anonymous Online Contributor