Genetic Testing for Breast Cancer
This study is evaluating whether genetic testing can predict tumor response in patients with stage I-III HER2 negative invasive breast cancer.
See full descriptionAbout the trial for Breast Cancer
Treatment Groups
This trial involves 2 different treatments. Genetic Testing is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
About The Treatment
Eligibility
This trial is for female patients aged 18 and older. You must have received 1 prior treatment for Breast Cancer or one of the other 23 conditions listed above. There are 2 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Genetic Testing will improve 1 primary outcome and 4 secondary outcomes in patients with Breast Cancer. Measurement will happen over the course of Up to 5 years.
Patient Q & A Section
What causes breast cancer?
These case-control studies provide information on potential environmental explanations for many aspects of breast cancer incidence. However, this information cannot be used to deduce the mechanism by which breast cancer occurs.
Can breast cancer be cured?
There is a very small chance that breast cancer may be cured. However, in those couples where both partners have had breast cancer and have survived long enough with no history of recurrence, the couple may actually develop and endure a life without breast cancer.
What is breast cancer?
Breast cancer is the main cancer that affects women in Europe and poses a major public health problem. This article presents information to the public for patients and clinicians concerning breast cancer.
What are common treatments for breast cancer?
There is no 'gold standard'. Some patients with breast cancer may be treated for only a short time with no effect, while others remain metastatic and have poorer outcomes despite new therapies. The timing and length of treatment has an important effect on a patient's outcome.
What are the signs of breast cancer?
Symptoms of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) mostly occur when the cancer has has metastasized. Breast cancer is often diagnosed by a physician only when its presence is suspected prior to or during a health check-up in which a mammogram is carried out. Symptoms of breast cancer include a lump or a lump and a painless mass in one breast. If there are symptoms or in a health check-up a physician should be alerted.\n
How many people get breast cancer a year in the United States?
The American Cancer Society estimates 254,300 new diagnoses of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) will be made in 2022. At the same time, the number of new breast cancer cases in the United States may be about 1.2 million annually.
Is genetic testing typically used in combination with any other treatments?
The use of genetic testing is a relatively recent practice and is not yet common practice. The current practice of using genetic testing in combination with treatments may change as the potential benefits and cost become better understood. The potential benefits of improved prognostic information, response monitoring and treatment personalisation include: improving adherence to and adherence to treatment, reducing the need for invasive procedures and reducing costs. These outcomes are critical considerations when considering the value of genetic testing.
How quickly does breast cancer spread?
It is a common phenomenon that once tumour cells have migrated from primary tumour site to lymph node, it quickly spread to other tissues and then spread to primary tumour site. It takes on average one to two months for the metastasis of the primary tumour site to be felt.
Have there been any new discoveries for treating breast cancer?
The most recent studies have not added much (if any) to breast cancer surgery. On the contrary, some of the current new findings are harmful for patients. Current research has led to the development of new pharmaceuticals, but these can be harmful as well.
What are the common side effects of genetic testing?
The side effects of genetic testing vary by the type and location of the tests performed and by the individuals being tested. As test accuracy is improved, adverse effects may also evolve. A better understanding of what adverse experiences prospective patients are likely to encounter, particularly those who have had previous adverse experiences from earlier tests, may lead to greater satisfaction, and reduce concerns and risks.
Have there been other clinical trials involving genetic testing?
Patients with a family history of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) and other manifestations suggestive of hereditary syndromes may be investigated by clinical oncologists. Gene testing may confirm the existence of hereditary breast cancer in these patients. This genetic testing can identify at-risk individuals in order to obtain a more complete pedigree by inviting them--or their relatives--for testing. These tests have not been in routine clinical use, but may be helpful in a select number of cases for which it is appropriate. Genetic testing may be indicated for women with high grade breast cancer in whom clinical evaluation does not reveal any identifiable family history of breast or other cancers.
What is the primary cause of breast cancer?
Results from a recent clinical trial has demonstrated that the likelihood of breast cancer occurrence is significantly higher in some ethnic groups compared with others. Also it was found that the number of live births per female was higher in women with a family history of breast cancer, and this was independent of ethnicity.