This trial is studying how well lower-dose chemotherapy + radiation works to treat patients with early-stage anal cancer, compared to standard-dose chemoradiation.
- Stage IIA Anal Cancer
- Anal Basaloid Carcinoma
- Anal Squamous Cell Carcinoma
- Anal Cancer
- Stage I Anal Cancer
- Anal Canal Cloacogenic Carcinoma
2 Primary · 17 Secondary · Reporting Duration: Up to 5 years
Awards & Highlights
2 Treatment Groups
Arm A (standard-dose chemoradiation)
1 of 2
Arm B (de-intensified chemoradiation)
1 of 2
252 Total Participants · 2 Treatment Groups
Primary Treatment: Intensity-Modulated Radiation Therapy · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
What state do they live in?
What portion of applicants met pre-screening criteria?
|Did not meet criteria||100.0%|
Why did patients apply to this trial?
- "I have anal prolapse sometimes"
How many prior treatments have patients received?
Frequently Asked Questions
What are the potential adverse effects of receiving Intensity-Modulated Radiation Therapy?
"The safety of Intensity-Modulated Radiation Therapy was given a rating of 2, as clinical trials thus far have provided evidence that it is safe but not yet proven to be effective." - Anonymous Online Contributor
What medical conditions can be treated through Intensity-Modulated Radiation Therapy?
"Intensity-Modulated Radiation Therapy is a viable treatment option for those suffering from head and neck carcinoma, cervical cancers, and glaucoma." - Anonymous Online Contributor
How many geographical locations are administering this trial?
"This investigation is being conducted at Marshfield Medical Center-EC Cancer Centre in Eau Claire, Wisconsin; Munson Medical Center in Traverse City, Michigan; and Kootenai Clinic Cancer Services - Post Falls in Post Falls, Idaho. There are 100 other locations participating as well." - Anonymous Online Contributor
Has Intensity-Modulated Radiation Therapy been investigated in other trials?
"The number of live studies for Intensity-Modulated Radiation Therapy stands at 620 with 211 trials in Phase 3. Woolloongabba, Queensland is the epicenter of this research activity, yet 25537 locations globally are conducting related clinical studies." - Anonymous Online Contributor
Is it still feasible for individuals to enroll in this clinical experiment?
"Affirmative. Clinicaltrials.gov details that this medical trial, which was established on November 12th 2019, is actively looking for participants. 252 individuals are needed from 100 different sites to complete the study." - Anonymous Online Contributor
How many participants is the research team looking to recruit for this experiment?
"In order to advance this clinical trial, 252 patients meeting the specified requirements must be enrolled. Current locations for participants include Marshfield Medical Center-EC Cancer Centre in Eau Claire, Wisconsin and Munson Medical Centre in Traverse City, Michigan." - Anonymous Online Contributor