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Immunotherapy + Electroporation for Pancreatic Cancer
Study Summary
This trial is testing a new treatment for pancreatic cancer that uses electric fields to kill cancer cells. The treatment is being given with nivolumab, which is a immunotherapy drug.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am 18 years old or older.My condition is stage III pancreatic cancer.I had a heart attack in the last 3 months.I have metal implants near my cancer that cannot be removed.
- Group 1: Single Arm
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any research endeavors that have focused on Nivolumab?
"Currently, 82 trials for Nivolumab are in the third phase of research and development, out of a total 718 active studies. Most trials for this drug take place in Basel, BE; however there are 40237 sites offering clinical testing worldwide."
Has a comparable study of this type been conducted before?
"Presently, 718 active studies on Nivolumab have been organized in 2354 cities and 49 nations. This medication was first tested for efficacy back in 2012 by Ono Pharmaceutical Co. Ltd with a Phase 1 & 2 trial involving 659 patients. Since then, 255 additional trials have concluded."
What is the upper limit of participants for this experiment?
"Unfortunately, no more patients are being sought for this trial. It was first introduced on the 14th of August 2017 and most recently updated on October 24th 2022. For those looking to join an ongoing study, 787 clinical trials with adenocarcinoma as a focus and 718 studies involving Nivolumab remain in search of participants."
What has been the traditional application of Nivolumab?
"Nivolumab is suitable for the management of many malignant neoplasms, ranging from inoperable melanomas to metastatic esophageal adenocarcinoma and squamous cell carcinoma."
What unfavorable effects has Nivolumab been associated with?
"Considering the phase of this trial, there is enough evidence to suggest Nivolumab's safety merits a score of 2. Unfortunately, no trials have been conducted to confirm its efficacy as yet."
Are there still openings available for prospective subjects in this research endeavor?
"As per the information on clinicaltrials.gov, this study has finished recruiting participants. The trial was initially posted in August 2017 and last updated in October 2022. Nevertheless, at present there are 1,505 other medical studies actively seeking volunteers."
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