← Back to Search

Other

Group A: 4-aminopyridine for Skin Wound

Phase 2

Waitlist Available

Led By John Elfar, MD

Research Sponsored by John Elfar

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 weeks

Awards & highlights

Study Summary

"This trial aims to test a new treatment, 4-aminopyridine (4-AP), to see if it can help wounds heal faster in healthy adults."

Who is the study for?

This trial is for adults with chronic non-healing wounds or acute wounds. Participants should be in good health overall, aside from their wound condition.Check my eligibility

What is being tested?

The study tests if 4-aminopyridine (4-AP), a new agent thought to be safe, can speed up the healing of wounds. Some participants will receive 4-AP while others will get a placebo for comparison.See study design

What are the potential side effects?

While the safety profile of 4-AP is considered excellent, potential side effects are not detailed here and would depend on individual reactions to the treatment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Return of skin integrity and wound closure after skin punch biopsy

Secondary outcome measures

The effect of 4-AP on the hair number and growth at the skin punch biopsy site.

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Group A: 4-aminopyridineActive Control1 Intervention

dalfampridine (generic) 10 mg capsule po every 12 hours

Group II: Group B: PlaceboPlacebo Group1 Intervention

Placebo-1 capsule po every 12 hours

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

John ElfarLead Sponsor

2 Previous Clinical Trials

230 Total Patients Enrolled

John Elfar, MDPrincipal InvestigatorUniversity of Arizona

3 Previous Clinical Trials

298 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible for me to participate in this research study?

"Patients aged between 18 and 70 with wounds are eligible for inclusion in this study, which aims to recruit a total of 68 participants."

Answered by AI

Is this clinical trial currently seeking and enrolling participants?

"According to the details on clinicaltrials.gov, patient enrollment for this trial is not ongoing. The initial posting date was 1st July 2024 and the most recent update occurred on 20th March 2024. However, it's worth noting that while this study isn't actively enrolling participants presently, there are a noteworthy 849 other trials currently seeking volunteers."

Answered by AI

Is the eligibility criteria for this study limited to individuals aged 18 years and older?

"Patients within the age range of 18 to 70 are eligible for enrollment in this medical research study. For those under 18, there are a total of 155 clinical trials available, while individuals over the age of 65 have access to 689 studies."

Answered by AI

What are the safety considerations for Group A: 4-aminopyridine in regards to patient use?

"Our team at Power has assessed the safety of Group A: 4-aminopyridine to be a 2 on our scale, considering this is a Phase 2 trial without confirmed efficacy data but with some evidence supporting its safety."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

4-aminopyridine for Skin Wound Healing

John Elfar 2024. "4-aminopyridine for Skin Wound Healing". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06333171.